- PS-COD and PS-9-BBN: polymer-supported reagents for solution-phase parallel synthesis.
PS-COD and PS-9-BBN: polymer-supported reagents for solution-phase parallel synthesis.
Organic letters (2005-02-25)
Jefferson D Revell, Barbara Dörner, Peter D White, A Ganesan
PMID15727452
ABSTRACT
1,5-Cyclooctadiene was deprotonated under LICKOR conditions and reacted with Merrifield resin to afford an immobilized cyclooctadiene in high yield. This polymer is effective as a halogen scavenger, while hydroboration leads to a supported 9-BBN analogue. The latter exhibits similar regioselectivity to 9-BBN in olefin hydroboration. [reaction: see text]