- CAN-mediated oxidations for the synthesis of xanthones and related products.
CAN-mediated oxidations for the synthesis of xanthones and related products.
The Journal of organic chemistry (2010-11-23)
Myron M Johnson, Jeremy M Naidoo, Manuel A Fernandes, Edwin M Mmutlane, Willem A L van Otterlo, Charles B de Koning
PMID21086958
ABSTRACT
Reaction of (2,4,5-trimethoxyphenyl)(2-hydroxyphenyl)methanone with ceric ammonium nitrate furnished the xanthone, 2,3-dimethoxy-9H-xanthen-9-one. Under the same conditions the related (1,4-dimethoxynaphthalen-2-yl)(2-hydroxyphenyl)methanone resulted in the formation of 12a-methoxy-5H-benzo[c]xanthenes 5,7(12aH)-dione. Other examples of this novel transformation are also outlined.
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