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  • Polyphosphoric acid promoted synthesis of 10,11-dihydrobenzo[j]fluoranthen-12-one.

Polyphosphoric acid promoted synthesis of 10,11-dihydrobenzo[j]fluoranthen-12-one.

Organic letters (2012-04-21)
Meng-Yang Chang, Tein-Wei Lee, Ming-Hao Wu
ABSTRACT

A straightforward synthesis of 3,8-dimethoxy-10,11-dihydrobenzo[j]fluoranthen-12-ones 1 is reported in a seven-step route from biphenyl-4,4'-diol 2 via the transformation of a double Claisen rearrangement, cross metathesis with ethyl acrylate, and polyphosphoric acid (PPA)-promoted Friedel-Crafts electrophilic benzannulation in good yields.

MATERIALS
Product Number
Brand
Product Description

Sigma-Aldrich
Polyphosphoric acid, ~105% H3PO4 basis
Sigma-Aldrich
Polyphosphoric acid, reagent grade, 115% H3PO4 basis