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  • Small intestinal transplant mucosal necrosis associated with enteral sodium polystyrene sulfonate administration.

Small intestinal transplant mucosal necrosis associated with enteral sodium polystyrene sulfonate administration.

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons (2012-08-21)
M Saginur, A Thiesen, A Lacson, D Bigam, J Yap
PMID22900907
ABSTRACT

Diarrhea is a common manifestation of disease in recipients of intestinal transplants. Sodium Polystyrene Sulfonate administration has been associated with significant bowel injury. Recognizing the diagnosis requires clinical awareness and comprehensive review of intestinal biopsies. We present an illustrative case and discussion. It is the first reported case in a pediatric intestinal transplant patient with serial intestinal biopsies documenting the evolution of disease.

MATERIALS
Product Number
Brand
Product Description
561223
Sigma-Aldrich
Poly(4-styrenesulfonic acid) solution, Mw ~75,000, 18 wt. % in H2O
527491
Sigma-Aldrich
Poly(sodium 4-styrenesulfonate) solution, average Mw ~1,000,000, 25 wt. % in H2O
527483
Sigma-Aldrich
Poly(sodium 4-styrenesulfonate) solution, average Mw ~70,000, 30 wt. % in H2O
434574
Sigma-Aldrich
Poly(sodium 4-styrenesulfonate), average Mw ~1,000,000, powder
243051
Sigma-Aldrich
Poly(sodium 4-styrenesulfonate), average Mw ~70,000
561967
Sigma-Aldrich
Poly(sodium 4-styrenesulfonate) solution, average Mw ~200,000, 30 wt. % in H2O