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  • Impact of sorbic acid on germination and outgrowth heterogeneity of Bacillus cereus ATCC 14579 spores.

Impact of sorbic acid on germination and outgrowth heterogeneity of Bacillus cereus ATCC 14579 spores.

Applied and environmental microbiology (2012-09-25)
Heidy M W den Besten, Clint C J van Melis, Jan Willem Sanders, Masja N Nierop Groot, Tjakko Abee
ABSTRACT

Population heterogeneity complicates the predictability of the outgrowth kinetics of individual spores. Flow cytometry sorting and monitoring of the germination and outgrowth of single dormant spores allowed the quantification of acid-induced spore population heterogeneity at pH 5.5 and in the presence of sorbic acid. This showed that germination efficiency was not a good predictor for heterogeneity in final outgrowth.

MATERIALS
Product Number
Brand
Product Description

Sigma-Aldrich
Sorbic acid, SAJ first grade, ≥98.5%
Sorbic acid, European Pharmacopoeia (EP) Reference Standard
Sigma-Aldrich
Sorbic acid, tested according to Ph. Eur.
Sigma-Aldrich
Sorbic acid, 99.0-101.0% anhydrous basis