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  • Triggering cell adhesion, migration or shape change with a dynamic surface coating.

Triggering cell adhesion, migration or shape change with a dynamic surface coating.

Advanced materials (Deerfield Beach, Fla.) (2013-01-29)
Stijn F M van Dongen, Paolo Maiuri, Emmanuelle Marie, Christophe Tribet, Matthieu Piel
ABSTRACT

There's an APP for that: cell-repellent APP (azido-[polylysine-g-PEG]) is used to create substrates for spatially controlled dynamic cell adhesion. The simple addition of a functional peptide to the culture medium rapidly triggers cell adhesion. This highly accessible yet powerful technique allows diverse applications, demonstrated through tissue motility assays, patterned coculturing and triggered cell shape change.

MATERIALS
Product Number
Brand
Product Description

Sigma-Aldrich
Arg-Gly-Asp, ≥97% (TLC)