- Synthesis, characterization, and antifungal activity of boron-containing thiosemicarbazones.
Synthesis, characterization, and antifungal activity of boron-containing thiosemicarbazones.
Chemistry & biodiversity (2008-11-28)
Justin W Hicks, Christian B Kyle, Christopher M Vogels, Susan L Wheaton, Felix J Baerlocher, Andreas Decken, Stephen A Westcott
PMID19035570
ABSTRACT
Addition of thiosemicarbazide, 4-allylthiosemicarbazide, and 4-phenylthiosemicarbazide to (formylphenyl)boronic acids affords a series of thiosemicarbazones containing boronic acids. Addition of 2-formylphenylboronic acid to the thiosemicarbazides gave the corresponding cyclic 2,3,1-benzodiazaborines. All new compounds have been investigated for potential antifungal activity.
MATERIALS