- Syntheses of novel heterocycles as anticancer agents.
Syntheses of novel heterocycles as anticancer agents.
Bioorganic & medicinal chemistry (2005-04-26)
Prem M S Chauhan, Cristina J A Martins, David C Horwell
PMID15848764
ABSTRACT
Several pteridine analogues 4-13, 23-26 have been synthesized and tested in vitro against three cancer cell lines, MCF7 (breast), NCI-H460 (lung) and SF-268 (CNS). All tested pteridines can serve as novel templates for the anticancer chemotherapy and can serve as new leads in cancer chemotherapy.
MATERIALS