- Efficient synthesis of aminopyridine derivatives by copper catalyzed amination reactions.
Efficient synthesis of aminopyridine derivatives by copper catalyzed amination reactions.
Chemical communications (Cambridge, England) (2010-01-29)
Mohammed K Elmkaddem, Cédric Fischmeister, Christophe M Thomas, Jean-Luc Renaud
PMID20107652
ABSTRACT
A copper(i) catalyzed amination reaction utilizing aqueous ammonia and operating under mild conditions is presented. This method was employed for the efficient synthesis of various aminopyridine derivatives bearing electron withdrawing and electron donating groups.
MATERIALS