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Highly Elastic and Conductive Human-Based Protein Hybrid Hydrogels.

Advanced materials (Deerfield Beach, Fla.) (2015-11-10)
Nasim Annabi, Su Ryon Shin, Ali Tamayol, Mario Miscuglio, Mohsen Afshar Bakooshli, Alexander Assmann, Pooria Mostafalu, Jeong-Yun Sun, Suzanne Mithieux, Louis Cheung, Xiaowu Shirley Tang, Anthony S Weiss, Ali Khademhosseini
ABSTRACT

A highly elastic hybrid hydrogel of methacryloyl-substituted recombinant human tropoelastin (MeTro) and graphene oxide (GO) nanoparticles are developed. The synergistic effect of these two materials significantly enhances both ultimate strain (250%), reversible rotation (9700°), and the fracture energy (38.8 ± 0.8 J m(-2) ) in the hybrid network. Furthermore, improved electrical signal propagation and subsequent contraction of the muscles connected by hybrid hydrogels are observed in ex vivo tests.

MATERIALS
Product Number
Brand
Product Description

Sigma-Aldrich
Tropoelastin human, recombinant, expressed in E. coli, 1 mg