Skip to Content
MilliporeSigma
All Photos(3)

Documents

106615

Sigma-Aldrich

2,2-Bis(hydroxymethyl)propionic acid

98%

Synonym(s):

Bis-MPA, DMPA®, Dimethylolpropionic acid

Sign Into View Organizational & Contract Pricing
All Photos(3)

About This Item

Linear Formula:
(HOCH2)2C(CH3)COOH
CAS Number:
4767-03-7
Molecular Weight:
134.13
Beilstein/REAXYS Number:
1756385
EC Number:
225-306-3
MDL number:
MFCD00004199
UNSPSC Code:
12352100
PubChem Substance ID:
24846739
NACRES:
NA.22

vapor density

<1 (vs air)

Quality Level

200

assay

98%

form

solid

mp

189-191 °C (lit.)

solubility

H2O: soluble
acetone: slightly soluble
benzene: insoluble
methanol: soluble

SMILES string

CC(CO)(CO)C(O)=O

InChI

1S/C5H10O4/c1-5(2-6,3-7)4(8)9/h6-7H,2-3H2,1H3,(H,8,9)

InChI key

PTBDIHRZYDMNKB-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

Related Categories

Application

2,2-Bis(hydroxymethyl)propionic acid based fourth generation tridendron dendrimer having 48 hydroxyl groups was synthesized.
2,2-Bis(hydroxymethyl)propionic acid is commonly used as an AB2 monomer for the synthesis of hyperbranched (hb) polymers and dendrimers.
2,2-Bis(hydroxymethyl)propionic acid was used in the synthesis and characterization studies of polyurethane dispersion modified with polymethylsiloxane (Si-PUD) and its nanocomposites incorporated with clays.2,2-Bis(hydroxymethyl)propionic acid based dendrimers have potent applications as delivery systems for potent anticancer drugs such as cisplatin and doxorubicin, as well as agents for both boron neutron capture therapy and photodynamic therapy.
Simple derivatives of this acid have been used to construct dendritic architectures via the "click" azide-acetylene cycloaddition.

Legal Information

DMPA is a registered trademark of GEO Specialty Chemicals, Inc.

pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H319

Hazard Classifications

Eye Irrit. 2

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

ppe

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Customers Also Viewed

Slide 1 of 3

1 of 3

Dimethyl 5-sulfoisophthalate sodium salt 98%

Sigma-Aldrich

150010

Dimethyl 5-sulfoisophthalate sodium salt

3-(2-Hydroxyethoxy)propanoic acid

Sigma-Aldrich

CDS021155

3-(2-Hydroxyethoxy)propanoic acid

Bis(pentafluorophenyl) carbonate 97%

Sigma-Aldrich

539899

Bis(pentafluorophenyl) carbonate

First divergent strategy using two AB2 unprotected monomers for the rapid synthesis of dendrimers.
Brauge L, et al.
Journal of the American Chemical Society, 123(27), 6698-6699 (2001)
Double-stage convergent approach for the synthesis of functionalized dendritic aliphatic polyesters based on 2, 2-bis (hydroxymethyl) propionic acid.
Ihre H and Hult A.
Macromolecules, 31(13), 4061-4068 (1998)
Kazuki Fukushima et al.
Biomaterials science, 7(6), 2288-2296 (2019-04-25)
Cationic aliphatic polycarbonates bearing primary ammonium side chains have been developed with relatively high molecular weights and controlled macromolecular architectures. These polycarbonates exhibit reasonable antimicrobial activity against Gram-negative and Gram-positive bacteria. The prepared homopolymers could be effective against Gram-negative bacteria
Structure buildup in hyperbranched polymers from 2, 2-bis (hydroxymethyl) propionic acid.
Magnusson H, et al.
Macromolecules, 33(8), 3099-3104 (2000)
Hui Dong et al.
Nanotechnology, 29(5), 055705-055705 (2017-12-13)
Amine-modified amphiphilic hyperbranched polymers (MePEG-H104-Nx) were prepared from hyperbranched 2,2-bis(methylol)propionic acid polyester (H104) by decoration with polyethylene glycol monomethyl ether (MePEG) and different classes of oligo(ethylenimine)s. By using the MePEG-H104-Nx polymers as stabilizers, gold nanoparticles (AuNPs) were prepared in an
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service