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129887

Sigma-Aldrich

N-Methylisatoic anhydride

technical, 90%

Synonym(s):

1-Methyl-1H -benzo[d ][1,3]oxazine-2,4-dione, 1-Methyl-4H -3,1-benzoxazine-2,4(1H )dione

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About This Item

Empirical Formula (Hill Notation):
C9H7NO3
CAS Number:
Molecular Weight:
177.16
EC Number:
MDL number:
UNSPSC Code:
12162002
PubChem Substance ID:
NACRES:
NA.23

vapor density

6.1 (vs air)

Quality Level

grade

technical

assay

90%

mp

165 °C (dec.) (lit.)

SMILES string

CN1C(=O)OC(=O)c2ccccc12

InChI

1S/C9H7NO3/c1-10-7-5-3-2-4-6(7)8(11)13-9(10)12/h2-5H,1H3

InChI key

KJMRWDHBVCNLTQ-UHFFFAOYSA-N

Related Categories

pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

wgk_germany

WGK 3

ppe

dust mask type N95 (US), Eyeshields, Gloves


Certificates of Analysis (COA)

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Kevin A Wilkinson et al.
Journal of the American Chemical Society, 127(13), 4659-4667 (2005-03-31)
Current models assume that RNA folding is strongly hierarchical such that the base-paired secondary structure is more stable than and forms independently of the tertiary structure. This model has been difficult to test due to the experimental inability to interrogate
Kady-Ann Steen et al.
Journal of the American Chemical Society, 134(32), 13160-13163 (2012-08-03)
Many RNA structures are composed of simple secondary structure elements linked by a few critical tertiary interactions. SHAPE chemistry has made interrogation of RNA dynamics at single-nucleotide resolution straightforward. However, de novo identification of nucleotides involved in tertiary interactions remains
Colby D Stoddard et al.
RNA (New York, N.Y.), 14(4), 675-684 (2008-02-13)
Riboswitches are highly structured cis-acting elements located in the 5'-untranslated region of messenger RNAs that directly bind small molecule metabolites to regulate gene expression. Structural and biochemical studies have revealed riboswitches experience significant ligand-dependent conformational changes that are coupled to
Joshua D Podlevsky et al.
RNA (New York, N.Y.), 22(2), 204-215 (2015-11-26)
Telomerase is a ribonucleoprotein (RNP) enzyme that requires an integral telomerase RNA (TR) subunit, in addition to the catalytic telomerase reverse transcriptase (TERT), for enzymatic function. The secondary structures of TRs from the three major groups of species, ciliates, fungi
Erich Smith-Peter et al.
RNA biology, 12(12), 1372-1382 (2015-09-26)
Riboswitches regulate gene expression by rearranging their structure upon metabolite binding. The lysine-sensing lysC riboswitch is a rare example of an RNA aptamer organized around a 5-way helical junction in which ligand binding is performed exclusively through nucleotides located at

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