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198102

Sigma-Aldrich

Sudan IV

Certified Biological Stain Commission,Dye content ≥80 %

Synonym(s):

Biebrich scarlet R fat soluble, Fat Ponceau R or 4, Lipid Crimson, Oil Red IV, Scarlet Red Scharlach, Solvent Red 24, Sudan R or BB

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About This Item

Empirical Formula (Hill Notation):
C24H20N4O
CAS Number:
85-83-6
Molecular Weight:
380.44
Colour Index Number:
26105
Beilstein/REAXYS Number:
709018
EC Number:
201-635-8
MDL number:
MFCD00003893
UNSPSC Code:
12171500
PubChem Substance ID:
24851862
NACRES:
NA.47

form

powder

Quality Level

100

composition

Certified Biological Stain Commission,Dye content, ≥80%

mp

199 °C (dec.) (lit.)

λmax

357 nm (2nd)
520 nm

ε (extinction coefficient)

≥12000 at 356-360 nm in toluene at 0.008 g/L
≥26000 at 519-523 nm in toluene at 0.008 g/L

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

room temp

SMILES string

Cc1ccccc1\N=N\c2ccc(\N=N\c3c(O)ccc4ccccc34)c(C)c2

InChI

1S/C24H20N4O/c1-16-7-3-6-10-21(16)26-25-19-12-13-22(17(2)15-19)27-28-24-20-9-5-4-8-18(20)11-14-23(24)29/h3-15,29H,1-2H3/b26-25+,28-27+

InChI key

RCTGMCJBQGBLKT-PAMTUDGESA-N

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General description

Sudan IV is a hydrophobic azo dye. It stains triglycerides and imparts an intense red color. The dye does not stain lipid droplets or phospholipids.

Application

Sudan IV has been used to in en-face staining of aorta, stains the lipid rich plaques. It has also been used to stain lipids atherosclerotic lesions of mice.

pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H317

Hazard Classifications

Skin Sens. 1A

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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The
Histophatologic Techniques (2006)
In Situ Remediation of Chlorinated Solvent Plumes (2010)
The induction of cytochrome P450 1A1 by Sudan dyes
Ahmed R, et al.
Journal of Biochemical and Molecular Toxicology, 22(2), 77-84 (2008)
Aorta atherosclerosis lesion analysis in hyperlipidemic mice
Mohanta S, et al.
Bio-protocol, 6(11), 77-84 (2016)
Discovery of a potent HMG-CoA reductase degrader that eliminates statin-induced reductase accumulation and lowers cholesterol
Jiang SY, et al.
Nature Communications, 9(1), 5138-5138 (2018)
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