Skip to Content
MilliporeSigma
All Photos(1)

Documents

234524

Sigma-Aldrich

O-Phenyl chlorothionoformate

99%

Synonym(s):

Phenyl thionochloroformate

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

Linear Formula:
ClC(S)OC6H5
CAS Number:
1005-56-7
Molecular Weight:
172.63
Beilstein/REAXYS Number:
774830
EC Number:
213-736-4
MDL number:
MFCD00004920
UNSPSC Code:
12352100
PubChem Substance ID:
24854046
NACRES:
NA.22

Quality Level

200

assay

99%

form

liquid

refractive index

n20/D 1.581 (lit.)

bp

81-83 °C/6 mmHg (lit.)

density

1.248 g/mL at 25 °C (lit.)

SMILES string

ClC(=S)Oc1ccccc1

InChI

1S/C7H5ClOS/c8-7(10)9-6-4-2-1-3-5-6/h1-5H

InChI key

KOSYAAIZOGNATQ-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

Related Categories

Application

O-Phenyl chlorothionoformate has been used in:
  • stereodirected synthesis of optically active, (−)-mintlactone
  • synthesis of peptide α-thioesters having a variety of C-terminal amino acids
  • synthesis of scyllo-inositol derivatives
  • thionocarbonylation of unprotected thymine nucleosides
  • preparation of phenoxythiocarbonyl esters of protected ribonucleosides

pictograms

Corrosion
GHS05

signalword

Danger

hcodes

H314

Hazard Classifications

Skin Corr. 1B

wgk_germany

WGK 3

flash_point_f

177.8 °F

flash_point_c

81 °C

ppe

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Synlett, 221-221 (1993)
Canadian Journal of Chemistry, 71, 186-186 (1993)
A synthetic approach to a peptide α-thioester from an unprotected peptide through cleavage and activation of a specific peptide bond by N-acetylguanidine.
Ryo Okamoto et al.
Angewandte Chemie (International ed. in English), 51(1), 191-196 (2011-11-19)
Total synthesis of (-)-mintlactone.
Carda M and Marco JA.
Tetrahedron Letters, 32(38), 5191-5192 (1991)
The Journal of Organic Chemistry, 58, 2552-2552 (1993)
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service