Skip to Content
MilliporeSigma
All Photos(1)

Documents

270792

Sigma-Aldrich

4-(Chloromethyl)benzoic acid

95%

Synonym(s):

α-Chloro-p-toluic acid, α-Chloro-p-toluylic acid

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

Empirical Formula (Hill Notation):
C8H7ClO2
CAS Number:
1642-81-5
Molecular Weight:
170.59
Beilstein/REAXYS Number:
1907970
EC Number:
216-697-1
MDL number:
MFCD00002568
UNSPSC Code:
12352100
PubChem Substance ID:
24856400
NACRES:
NA.22

Quality Level

200

assay

95%

form

powder

mp

201-202 °C (lit.)

SMILES string

OC(=O)c1ccc(CCl)cc1

InChI

1S/C8H7ClO2/c9-5-6-1-3-7(4-2-6)8(10)11/h1-4H,5H2,(H,10,11)

InChI key

OITNBJHJJGMFBN-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

Related Categories

Application

4-(Chloromethyl)benzoic acid was used in the synthesis of dihydroxy stilbene derivatives.

pictograms

Health hazardCorrosion
GHS08,GHS05

signalword

Danger

hcodes

H314,H334

Hazard Classifications

Eye Dam. 1 - Resp. Sens. 1 - Skin Corr. 1B

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Customers Also Viewed

Slide 1 of 5

1 of 5

Methyl 4-(bromomethyl)benzoate 98%

Sigma-Aldrich

348155

Methyl 4-(bromomethyl)benzoate

4-(Aminomethyl)benzoic acid 97%

Sigma-Aldrich

283746

4-(Aminomethyl)benzoic acid

4-Vinylbenzoic acid 97%

Sigma-Aldrich

254738

4-Vinylbenzoic acid

1-Methylpiperazine 99%

Sigma-Aldrich

130001

1-Methylpiperazine

Chlorobenzene anhydrous, 99.8%

Sigma-Aldrich

284513

Chlorobenzene

Sheng Yan et al.
Colloids and surfaces. B, Biointerfaces, 188, 110769-110769 (2020-01-10)
Polysulfone (PSf) membrane is widely employed in blood purification fields, but the blood compatibility of PSf membrane is not adequate. To improve the hemocompatibility of PSf membrane, 4-(chloromethyl)benzoic acid (CMBA) and sulfonated hydroxypropyl chitosan (SHPCS) were grafted onto PSf membrane
Marcela Silva Lopes et al.
Anti-cancer agents in medicinal chemistry, 15(2), 206-216 (2014-11-19)
Twenty-seven nitrated and non-nitrated compounds have been synthesized and tested for their growth inhibitory activity on three human cancer cells lines. Fourteen compounds were able to inhibit more than 50% of the growth of at least one of the cancer
Mankil Jung et al.
Bioorganic & medicinal chemistry letters, 17(16), 4481-4486 (2007-06-29)
Dihydroxy stilbene derivatives were designed based on lithospermic acid B and were prepared from 4-(chloromethyl)benzoic acid. The inhibitory activities of the novel compounds against protein tyrosine phosphatase 1B (PTP1B) were evaluated. 3,4-Dihydroxy stilbene carbonyl compounds (7, 11b, 27b) inhibited PTP1B
Yasuo Yoshimi et al.
Analytica chimica acta, 862, 77-85 (2015-02-16)
In this work, the anodic current at an electrode grafted with a molecularly imprinted polymer (MIP) crosslinked via a combination of hydrophobic ethyleneglycol dimethacrylate (EDMA) and hydrophilic methylene bisacrylamide (MBAA) was found to exhibit enantioselective sensitivity to the phenylalanine template

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service