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347957

Sigma-Aldrich

Glycine tert-butyl ester hydrochloride

97%

Synonym(s):

tert-Butyl aminoacetate hydrochloride

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About This Item

Linear Formula:
H2NCH2CO2C(CH3)3 · HCl
CAS Number:
Molecular Weight:
167.63
Beilstein/REAXYS Number:
3989048
MDL number:
UNSPSC Code:
12352209
eCl@ss:
32160406
PubChem Substance ID:
NACRES:
NA.22

Quality Level

assay

97%

form

powder

reaction suitability

reaction type: solution phase peptide synthesis

mp

141-143 °C (lit.)

application(s)

peptide synthesis

SMILES string

Cl.CC(C)(C)OC(=O)CN

InChI

1S/C6H13NO2.ClH/c1-6(2,3)9-5(8)4-7;/h4,7H2,1-3H3;1H

InChI key

OSWULUXZFOQIRU-UHFFFAOYSA-N

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Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Cross-linked polystyrene-bound and poly(ethylene glycol)-bound phase-transfer catalysts as well as homopolymers of cinchona alkaloid derivatives have been synthesised. Both soluble and insoluble polymers have been investigated. The enantioselective alkylation of N-diphenyl methylene glycine t-butyl ester has been successfully carried out
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[reaction: see text]. A chiral phase-transfer catalyst has been applied to the asymmetric allylation of the tert-butyl glycinate-benzophenone Schiff base with various allylic acetates for the first time to give the allylated products in good yields and with comparable to
S Sarhan et al.
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The synergistic amplification of the anticonvulsant effects of direct and indirect GABA agonists by glycine has previously been demonstrated. We show in the present report that the anticonvulsant effect of vinyl GABA, a GABA-T (4-aminobutyrate: 2-oxoglutarate aminotransferase) inhibitor with antiepileptic
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Chemical communications (Cambridge, England), 47(5), 1631-1633 (2010-12-01)
An efficient, catalytic, diastereo- and enantioselective conjugate addition of N-(diphenylmethylene)glycine tert-butyl ester to β-aryl substituted enones was realized in the presence of 1 mol% of newly desired dinuclear N-spiro-ammonium salts, affording functionalized α-amino acid derivatives in 57-98% yields with high
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Hirudin is the most potent and specific inhibitor of thrombin, a key enzyme in the coagulation process existing in equilibrium between its procoagulant (fast) and anticoagulant (slow) form. In a previous study, we described the solid-phase synthesis of a Trp3

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