Skip to Content
MilliporeSigma
All Photos(1)

Documents

374482

Sigma-Aldrich

N-Benzylquininium chloride

95%

Synonym(s):

QUIBEC

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

Empirical Formula (Hill Notation):
C27H31ClN2O2
CAS Number:
67174-25-8
Molecular Weight:
451.00
Beilstein/REAXYS Number:
5702637
MDL number:
MFCD00198105
UNSPSC Code:
12352005
PubChem Substance ID:
24863311
NACRES:
NA.22

Quality Level

100

assay

95%

optical activity

[α]20/D −235°, c = 1.5 in H2O

mp

200-205 °C (dec.) (lit.)

SMILES string

[Cl-].COc1ccc2nccc([C@@H](O)[C@@H]3C[C@@H]4CC[N@+]3(C[C@@H]4C=C)Cc5ccccc5)c2c1

InChI

1S/C27H31N2O2.ClH/c1-3-20-18-29(17-19-7-5-4-6-8-19)14-12-21(20)15-26(29)27(30)23-11-13-28-25-10-9-22(31-2)16-24(23)25;/h3-11,13,16,20-21,26-27,30H,1,12,14-15,17-18H2,2H3;1H/q+1;/p-1/t20-,21-,26-,27+,29+;/m0./s1

InChI key

JYDIJFKNXHPWBJ-GOGFHWEMSA-M

Looking for similar products? Visit Product Comparison Guide

Related Categories

General description

N-Benzylquininium chloride (or Quibec) belongs to the class of cinchona family of alkaloids. It is used as a catalyst in the presence of hydroxide bases in various phase transfer reactions, epoxidations, alkylations, and Michael reactions.

Application

N-Benzylquininium chloride can be used as a phase transfer catalyst:
  • In the sulfenylation of various β-keto sulfoxides.
  • To synthesize N-carbamoyl-protected β-nitroamines from α-amido sulfones by asymmetric aza-Henry reaction.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Phase-Transfer-Catalyzed Asymmetric Aza-Henry Reaction Using N-Carbamoyl Imines Generated In Situ from ?-Amido Sulfones
Fini F, et al.
Angewandte Chemie (International ed. in English), 44(48), 7975-7978 (2005)

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service