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466387

Sigma-Aldrich

Brij® S 100

average Mn ~4,670

Synonym(s):

Polyoxyethylene (100) stearyl ether

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About This Item

Linear Formula:
C18H37(OCH2CH2)nOH, n~100
CAS Number:
MDL number:
UNSPSC Code:
12162002
PubChem Substance ID:
NACRES:
NA.23

mol wt

average Mn ~4,670

Quality Level

mp

51-54 °C (lit.)

hydroxyl value

13‑25 mg KOH/g

solubility

propylene glycol and xylene: insoluble

density

1.1 g/mL at 25 °C (lit.)

HLB

18

InChI

1S/C20H41O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-19-22-20-18-21/h2-20H2,1H3

InChI key

PSEGVHKUPXNGGJ-UHFFFAOYSA-N

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Application

Brij® S 100 may be used:
  • as a non-ionic surfactant to study its interactions with luminol electrochemiluminescence for bioanalysis
  • as a carrier material to study the formulation of nimodipine, fenofibrate, and o-vanillin using the particles from gas-saturated solution (PGSS) process
  • as a hydrophilic surfactant in the casting solution to prepare an asymmetric flat sheet nanofiltration membranes and to study its effects on the hydrophilic property of the poly(ethersulfone) (PES) nanofiltration membranes

Legal Information

Brij is a registered trademark of Croda International PLC

pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Acute Tox. 4 Oral

wgk_germany

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Brij® L23 main component: tricosaethylene glycol dodecyl ether

Sigma-Aldrich

16005

Brij® L23

USP

USP

1547550

Polyoxyl 100 stearate

Brij® 35 for synthesis

Sigma-Aldrich

8.01962

Brij® 35

S Rahima Benhabbour et al.
Journal of controlled release : official journal of the Controlled Release Society, 158(1), 63-71 (2011-11-01)
Lipid-based oil-filled nanoparticles (NPs) with a high concentration of surface-chelated nickel (Ni-NPs) were successfully prepared using a Brij 78-NTA-Ni conjugate synthesized with Brij 78 (Polyoxyethylene (20) stearyl ether) and nitrilotriacetic acid (NTA). The facile incorporation of the Brij 78-NTA-Ni conjugate
L Realini et al.
Journal of clinical microbiology, 35(11), 2791-2794 (1997-11-14)
We report on the influences of polyoxyethylene stearate (POES), PANTA, and pH on primary cultures of Mycobacterium genavense in BACTEC vials. As a model for primary cultures from tissue, seven different strains first isolated from AIDS patients (five from Switzerland
S X Liu et al.
Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 11(3), 279-282 (1995-01-01)
Although sufficient amount of glucagon can be taken up into systemic circulation through ocular route, the concentration of eyedrops needed at 7.5% would be too high and the price of the doses would be too expensive to be desirable. Attempts
Jigna D Patel et al.
Pharmaceutical research, 24(2), 343-352 (2006-12-21)
The purpose of these studies was to prepare nanoparticles (NPs) with a small amount of surface-chelated nickel for obtaining enhanced binding of histidine-tagged (his-tag) proteins compared to non-histidine-tagged protein binding to charged nanoparticles. NPs were prepared from oil-in-water microemulsion precursors
Tatsuaki Tagami et al.
Journal of controlled release : official journal of the Controlled Release Society, 152(2), 303-309 (2011-02-23)
We have developed a novel and simplified thermosensitive liposomal formulation (HaT: Hyperthermia-activated cytoToxic) composed of DPPC lipid and Brij78 (96:4, molar ratio). The HaT nanoparticles were loaded with doxorubicin (DOX) with >95% efficiency when a pH gradient method and a

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