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534390

Sigma-Aldrich

N-Boc-trans-4-N-Fmoc-amino-L-proline

97%

Synonym(s):

(2S,4R)-N-(tert-Butoxycarbonyl)-4-N-(9-fluorenylmethoxycarbonyl)aminopyrrolidine-2-carboxylic acid

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About This Item

Empirical Formula (Hill Notation):
C25H28N2O6
CAS Number:
Molecular Weight:
452.50
MDL number:
UNSPSC Code:
12352209
PubChem Substance ID:
NACRES:
NA.26

Quality Level

assay

97%

optical activity

[α]20/D −34°, c = 1 in chloroform

reaction suitability

reaction type: Boc solid-phase peptide synthesis

mp

199 °C (lit.)

application(s)

peptide synthesis

functional group

Boc
Fmoc

SMILES string

CC(C)(C)OC(=O)N1C[C@@H](C[C@H]1C(O)=O)NC(=O)OCC2c3ccccc3-c4ccccc24

InChI

1S/C25H28N2O6/c1-25(2,3)33-24(31)27-13-15(12-21(27)22(28)29)26-23(30)32-14-20-18-10-6-4-8-16(18)17-9-5-7-11-19(17)20/h4-11,15,20-21H,12-14H2,1-3H3,(H,26,30)(H,28,29)/t15-,21+/m1/s1

InChI key

UPXRTVAIJMUAQR-VFNWGFHPSA-N

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


Certificates of Analysis (COA)

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Articles

Proline analogues are promising candidates for tuning the biological, pharmaceutical, or physicochemical properties of naturally occuring, as well as de novo designed, linear, and, cyclic peptides.

Proline analogues are promising candidates for tuning the biological, pharmaceutical, or physicochemical properties of naturally occuring, as well as de novo designed, linear, and, cyclic peptides.

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