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Sigma-Aldrich

N-(2-Aminoethyl)maleimide trifluoroacetate salt

≥95% (HPLC), ≥98% (T)

Synonym(s):

2-Maleimidoethylamine trifluoroacetate salt

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About This Item

Empirical Formula (Hill Notation):
C6H8N2O2 · C2HF3O2
CAS Number:
146474-00-2
Molecular Weight:
254.16
MDL number:
MFCD01073617
UNSPSC Code:
12161502
PubChem Substance ID:
57651612
NACRES:
NA.22

Quality Level

100

assay

≥95% (HPLC)
≥98% (T)

form

powder

reaction suitability

reagent type: cross-linking reagent
reagent type: linker

functional group

amine
maleimide

polymer architecture

functionality: heterobifunctional

SMILES string

OC(C(F)(F)F)=O.O=C1N(CCN)C(C=C1)=O

InChI

1S/C6H8N2O2.C2HF3O2/c7-3-4-8-5(9)1-2-6(8)10;3-2(4,5)1(6)7/h1-2H,3-4,7H2;(H,6,7)

InChI key

YNHKVOGCDPODMT-UHFFFAOYSA-N

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General description

N-(2-Aminoethyl)maleimide trifluoroacetate salt is a thiol reactive cross-linking agent used in the preparation of heparin hydrogels

Application

N-(2-Aminoethyl)maleimide trifluoroacetate salt commonly utilized:
  • As a crosslinking agent to form covalent bonds between polymeric precursors
  • In the synthesis of maleimide-functionalized heparin hydrogels by introducing maleimide functional groups to molecules, enabling subsequent bioconjugation
  • In the synthesis of N-(2-{3-Iodobenzoyl}aminoethyl)maleimide and N-(2-{3-(tri-n-Butylstannyl)benzoyl}aminoethyl)maleimide
  • As a building block in the synthesis of maleimide-functionalized cymantrenyl derivatives

Other Notes

Heterobifunctional linker for introducing a maleimide function into the widely used NOSu-modified fluorescent labels.

pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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