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600113

Sigma-Aldrich

L-Arginine-15N4 hydrochloride

98 atom % 15N, 97% (CP)

Synonym(s):

SILAC Amino Acid, (S)-(+)-Arginine hydrochloride-15N4, 15N Labeled arginine hydrochloride

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About This Item

Linear Formula:
H215NC(15NH)15NH(CH2)3C(15NH2)CO2H · HCl
CAS Number:
204633-95-4
Molecular Weight:
214.64
MDL number:
MFCD00144559
UNSPSC Code:
12352209
PubChem Substance ID:
24881774
NACRES:
NA.12

isotopic purity

98 atom % 15N

Quality Level

200

assay

≥97% (Chiral Purity)
97% (CP)

form

solid

optical activity

[α]20/D +22°, c = 12 in 10% HCl

technique(s)

bio NMR: suitable
protein expression: suitable

mp

226-230 °C (dec.) (lit.)

mass shift

M+4

SMILES string

Cl[H].[15NH2][C@@H](CCC[15NH]C([15NH2])=[15NH])C(O)=O

InChI

1S/C6H14N4O2.ClH/c7-4(5(11)12)2-1-3-10-6(8)9;/h4H,1-3,7H2,(H,11,12)(H4,8,9,10);1H/t4-;/m0./s1/i7+1,8+1,9+1,10+1;

InChI key

KWTQSFXGGICVPE-JYJSWXFRSA-N

Related Categories

General description

Arginine is an amino acid with a basic side group. In liver, arginine is cleaved to ornithine and urea. Isotope labeled amino acids are required for the production of isotopically labeled proteins.

Application

L-Arginine-15N4 hydrochloride has been used as a supplement for growing rat hybridoma to generate 15N-labeled monoclonal antibody against GPIHBP1 (glycosylphosphatidylinositol-anchored HDL binding protein 1).

Packaging

This product may be available from bulk stock and can be packaged on demand. For information on pricing, availability and packaging, please contact Stable Isotopes Customer Service.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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High-resolution imaging of dietary lipids in cells and tissues by NanoSIMS analysis.
Jiang H, et al.
Journal of Lipid Research, 55, 2156-2166 (2014)
Harvey RA, et al.
Biochemistry (Lippincott's illustrated reviews) (2011)
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Incorporation of radioactive amino acids into proteins of the microsome fraction of guinea-pig liver in a cell-free system.
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The incorporation of radioactive amino acids into proteins of the microsome fraction of guinea-pig liver at very short time intervals after administration.
Simkin JL and Sutton CR
The Biochemical Journal, 77, 489-492 (1960)

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