615609
Indole-2,4,5,6,7-d5-3-acetic-2,2-d2 acid
97 atom % D
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About This Item
Empirical Formula (Hill Notation):
C10D7H2NO2
Molecular Weight:
182.23
MDL number:
UNSPSC Code:
12352005
PubChem Substance ID:
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isotopic purity
97 atom % D
form
solid
technique(s)
mass spectrometry (MS): suitable
mp
165-169 °C (lit.)
mass shift
M+7
SMILES string
[2H]c1[nH]c2c([2H])c([2H])c([2H])c([2H])c2c1C([2H])([2H])C(O)=O
InChI
1S/C10H9NO2/c12-10(13)5-7-6-11-9-4-2-1-3-8(7)9/h1-4,6,11H,5H2,(H,12,13)/i1D,2D,3D,4D,5D2,6D
InChI key
SEOVTRFCIGRIMH-PYNXLSDISA-N
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Teresa Zelante et al.
Cell reports, 34(4), 108673-108673 (2021-01-28)
Indoleamine 2,3-dioxygenases (IDOs) degrade l-tryptophan to kynurenines and drive the de novo synthesis of nicotinamide adenine dinucleotide. Unsurprisingly, various invertebrates, vertebrates, and even fungi produce IDO. In mammals, IDO1 also serves as a homeostatic regulator, modulating immune response to infection
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