Skip to Content
MilliporeSigma
All Photos(3)

Documents

651664

Sigma-Aldrich

Tetrabutylammonium azide

Synonym(s):

N,N,N-Tributyl-1-butanaminium azide, Tetrabutylammonium nitride

Sign Into View Organizational & Contract Pricing
All Photos(3)

About This Item

Empirical Formula (Hill Notation):
C16H36N4
CAS Number:
993-22-6
Molecular Weight:
284.48
MDL number:
MFCD00060069
UNSPSC Code:
12352116
PubChem Substance ID:
24883851
NACRES:
NA.22

form

solid

Quality Level

200

reaction suitability

reaction type: click chemistry

mp

84-88 °C (lit.)

storage temp.

2-8°C

SMILES string

[N-]=[N+]=[N-].CCCC[N+](CCCC)(CCCC)CCCC

InChI

1S/C16H36N.N3/c1-5-9-13-17(14-10-6-2,15-11-7-3)16-12-8-4;1-3-2/h5-16H2,1-4H3;/q+1;-1

InChI key

GMRIOAVKKGNMMV-UHFFFAOYSA-N

Related Categories

Application

Reagent for synthesis of:
  • Heteroarylannulated bicyclic morpholines
  • Cyanimide-based inhibitors of cathepsin C
  • Trimethylene carbonate

Reagent for:
  • Aerobic oxidative transformation of primary azides to nitriles
  • Substitution reactions at tetracoordinate boron

Catalyst for syslic carbonate formation
Tetrabutylammonium azide can be used as a reagent for the synthesis of:
  • Heteroarylannulated bicyclic morpholines
  • Cyanimide-based inhibitors of cathepsin C
  • Trimethylene carbonate
  • Aerobic oxidative transformation of primary azides to nitriles
  • Substitution reactions at tetracoordinate boron


It is also used as a catalyst for cyclic carbonate formation.

pictograms

Skull and crossbonesEnvironment
GHS06,GHS09

signalword

Danger

Hazard Classifications

Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

supp_hazards

EUH032

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

A facile catalytic synthesis of trimethylene carbonate from trimethylene oxide and carbon dioxide.
Darensbourg DJ, et al.
Green Chemistry, 12(8), 1376-1379 (2010)
Substitution Reactions at Tetracoordinate Boron: Synthesis of N-Heterocyclic Carbene Boranes with Boron- Heteroatom Bonds.
Solovyev A, et al.
Journal of the American Chemical Society, 132(42), 15072-15080 (2010)
Aerobic oxidative transformation of primary azides to nitriles by ruthenium hydroxide catalyst.
He J, et al.
The Journal of Organic Chemistry, 76(11), 4606-4610 (2011)
Synthesis of bicyclic sugar azido acids and their incorporation in cyclic peptides.
Peri F, et al.
Chemical Communications (Cambridge, England), 2303-2304 (2000)
Mark Furber et al.
Journal of medicinal chemistry, 57(6), 2357-2367 (2014-03-07)
A lead generation and optimization program delivered the highly selective and potent CatC inhibitor 10 as an in vivo tool compound and potential development candidate. Structural studies were undertaken to generate SAR understanding.
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service