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69066

Sigma-Aldrich

Calix[8]arene

technical, ≥90% (CH)

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About This Item

Empirical Formula (Hill Notation):
C56H48O8
CAS Number:
82452-93-5
Molecular Weight:
848.98
MDL number:
MFCD04973078
UNSPSC Code:
12352002
PubChem Substance ID:
57652172
NACRES:
NA.22

grade

technical

Quality Level

100

assay

≥90% (CH)

form

powder

SMILES string

Oc1c2Cc3cccc(Cc4cccc(Cc5cccc(Cc6cccc(Cc7cccc(Cc8cccc(Cc9cccc(Cc1ccc2)c9O)c8O)c7O)c6O)c5O)c4O)c3O

InChI

1S/C56H48O8/c57-49-33-9-1-10-34(49)26-36-12-3-14-38(51(36)59)28-40-16-5-18-42(53(40)61)30-44-20-7-22-46(55(44)63)32-48-24-8-23-47(56(48)64)31-45-21-6-19-43(54(45)62)29-41-17-4-15-39(52(41)60)27-37-13-2-11-35(25-33)50(37)58/h1-24,57-64H,25-32H2

InChI key

HDPRHRZFFPXZIL-UHFFFAOYSA-N

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Application

Calix[8]arene can be used:
  • To prepare water-soluble glycocalix[8]arenes, which are used as model compounds to study the carbohydrate-protein binding interactions.
  • As a starting material in the synthesis of calix[8]arene sulfonic acids of biological importance.
  • As a ligand in the synthesis of tetranuclear calix[8]arene bismuth complexes.

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Calix[8] arene-based glycoconjugates as multivalent carbohydrate-presenting systems
Consoli GML, et al.
Tetrahedron Letters, 44(40), 7467-7470 (2003)
Design, synthesis and anticoagulant activity of new flexible calix [8] arene sulfonic acids
Rekkab S, et al.
Comptes Rendus Chimie, 16(7), 672-678 (2013)
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Adeno-associated virus (AAV) is a safe and effective vector for gene therapy for retinal disorders. Gene therapy for hearing disorders is not as advanced, in part because gene delivery to sensory hair cells of the inner ear is inefficient. Although
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Eukaryotic cells adapt their metabolism to the extracellular environment. Downregulation of surface cargo proteins in response to nutrient stress reduces the burden of anabolic processes whilst elevating catabolic production in the lysosome. We show that glucose starvation in yeast triggers
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