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700150

Sigma-Aldrich

(S)-Boc-5-oxopyrrolidine-2-carboxylic acid

97%

Synonym(s):

(−)-1-Boc-L-pyroglutamic acid, Boc-pyr-OH

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About This Item

Empirical Formula (Hill Notation):
C10H15NO5
CAS Number:
Molecular Weight:
229.23
EC Number:
MDL number:
UNSPSC Code:
12352106
PubChem Substance ID:
NACRES:
NA.22

Quality Level

assay

97%

form

powder

optical activity

[α]22/D −35.0, c = 1 in chloroform

reaction suitability

reaction type: Boc solid-phase peptide synthesis

mp

118-123 °C (dec.)

application(s)

peptide synthesis

storage temp.

−20°C

SMILES string

CC(C)(C)OC(=O)N1[C@@H](CCC1=O)C(O)=O

InChI

1S/C10H15NO5/c1-10(2,3)16-9(15)11-6(8(13)14)4-5-7(11)12/h6H,4-5H2,1-3H3,(H,13,14)/t6-/m0/s1

InChI key

MJLQPFJGZTYCMH-LURJTMIESA-N

pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves


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Qiuyu Gong et al.
Advanced science (Weinheim, Baden-Wurttemberg, Germany), 5(4), 1700664-1700664 (2018-05-04)
Previous study showed that pyroglutamate aminopeptidase 1 (PGP-1) has a relationship with the immune response in cells. However, whether PGP-1 is involved in inflammatory response in vivo and can serve as a new inflammatory cytokine are still unclear. To address

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