Skip to Content
MilliporeSigma
All Photos(3)

Documents

702757

Sigma-Aldrich

Potassium tert-pentoxide solution

2 M in THF

Synonym(s):

Potassium tert-amylate, Potassium (2-methyl-2-butoxide), Potassium tert-pentylate

Sign Into View Organizational & Contract Pricing
All Photos(3)

About This Item

Linear Formula:
CH3CH2C(CH3)2OK
CAS Number:
41233-93-6
Molecular Weight:
126.24
Beilstein/REAXYS Number:
4149025
MDL number:
MFCD00064808
UNSPSC Code:
12352001
PubChem Substance ID:
329762401
NACRES:
NA.22

form

liquid

Quality Level

100

concentration

2 M in THF

density

0.920 g/mL at 25 °C

SMILES string

[K+].CCC(C)(C)[O-]

InChI

1S/C5H11O.K/c1-4-5(2,3)6;/h4H2,1-3H3;/q-1;+1

InChI key

ZRLVQFQTCMUIRM-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

Related Categories

General description

Potassiumtert-pentoxide solution is a strong and sterically hindered alkoxide baseprepared by treating oil-free potassium hydride with anhydrous t-pentylalcohol in anhydrous solvent.

Application

Potassium tert-pentoxide solution can be used as a base in the:
  • Wittig reaction of ketoesters with methyltriphenylphosphonium bromide to synthesize alkenes.
  • Palladium-catalyzed Buchwald-Hartwig amination reaction.
It can also be used:
  • To prepare potassium tert-pentoxide-crown ether complexes, which is used as a Lewis base catalyst in Mukaiyama aldol reaction.
  • As an activator for (difluoromethyl)trimethylsilane to generate difluoromethyl-carbanion which reacts with isothiocyanate to synthesize α, α-difluoromethyl thioamide.

Features and Benefits

In the absence of air and moisture, potassium tert-pentoxide solutions in benzene or toluene may be stored in a refrigerator for up to 1 year without significant deterioration.

signalword

Danger

Hazard Classifications

Acute Tox. 4 Oral - Carc. 2 - Eye Dam. 1 - Flam. Liq. 2 - Skin Corr. 1B

supp_hazards

EUH019

Storage Class

3 - Flammable liquids

wgk_germany

WGK 3

flash_point_f

1.4 °F - Solvent

flash_point_c

-17 °C - Solvent

ppe

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Customers Also Viewed

Slide 1 of 8

1 of 8

Potassium tert-butoxide sublimed grade, 99.99% trace metals basis

Sigma-Aldrich

659878

Potassium tert-butoxide

Methyltriphenylphosphonium bromide 98%

Sigma-Aldrich

130079

Methyltriphenylphosphonium bromide

Sodium tert-butoxide 99.9%

Sigma-Aldrich

703788

Sodium tert-butoxide

Lithium tert-butoxide 97%

Sigma-Aldrich

400173

Lithium tert-butoxide

Sodium tert-butoxide 97%

Sigma-Aldrich

359270

Sodium tert-butoxide

2-Methyl-2-butene ≥95.0% (GC)

Sigma-Aldrich

86262

2-Methyl-2-butene

Potassium bis(trimethylsilyl)amide solution 1 M in THF

Sigma-Aldrich

702722

Potassium bis(trimethylsilyl)amide solution

Dess-Martin periodinane 97%

Sigma-Aldrich

274623

Dess-Martin periodinane

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service