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Sigma-Aldrich

Poly(ethylene glycol) dimethacrylate

average MN 10,000, cross-linking reagent polymerization reactions, methacrylate, ≤1, 500 ppm MEHQ as inhibitor (may contain)

Synonym(s):

Polyethylene glycol, PEG dimethacrylate

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About This Item

Linear Formula:
C3H5C(O)(OCH2CH2)nOC(O)C3H5
CAS Number:
MDL number:
UNSPSC Code:
12162002
NACRES:
NA.23

product name

Poly(ethylene glycol) dimethacrylate, average Mn 10,000, contains MEHQ as inhibitor

form

powder

mol wt

average Mn 10,000

contains

MEHQ as inhibitor
≤1,500 ppm MEHQ as inhibitor (may contain)

reaction suitability

reagent type: cross-linking reagent
reaction type: Polymerization Reactions

bp

>200 °C/2 mmHg (lit.)

transition temp

Tm 56-61 °C

Mw/Mn

≤1.1

Ω-end

methacrylate

α-end

methacrylate

polymer architecture

shape: linear
functionality: homobifunctional

storage temp.

−20°C

SMILES string

OCCO.CC(=C)C(O)=O

InChI

1S/C10H14O4/c1-7(2)9(11)13-5-6-14-10(12)8(3)4/h1,3,5-6H2,2,4H3

InChI key

STVZJERGLQHEKB-UHFFFAOYSA-N

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Preparation Note

Synthesized with an initial concentration of ≤1,500 ppm MEHQ

wgk_germany

WGK 1


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Pelagie M Favi et al.
Materials science & engineering. C, Materials for biological applications, 33(4), 1935-1944 (2013-03-19)
The culture of multipotent mesenchymal stem cells on natural biopolymers holds great promise for treatments of connective tissue disorders such as osteoarthritis. The safety and performance of such therapies relies on the systematic in vitro evaluation of the developed stem
C Aulin et al.
Laboratory animals, 47(1), 58-65 (2013-03-08)
Articular cartilage has a limited capacity for self-repair in adult humans, and methods used to stimulate regeneration often result in re-growth of fibrous cartilage, which has lower durability. No current treatment option can provide complete repair. The possibility of growth
Alyssa J Reiffel et al.
PloS one, 8(2), e56506-e56506 (2013-02-26)
Autologous techniques for the reconstruction of pediatric microtia often result in suboptimal aesthetic outcomes and morbidity at the costal cartilage donor site. We therefore sought to combine digital photogrammetry with CAD/CAM techniques to develop collagen type I hydrogel scaffolds and
Xuan Mu et al.
Lab on a chip, 13(8), 1612-1618 (2013-03-05)
Engineering functional vascular networks in vitro is critical for tissue engineering and a variety of applications. There is still a general lack of straightforward approaches for recapitulating specific structures and functions of vasculature. This report describes a microfluidic method that
[Manufacture of hydrogel-based phantoms of biological tissues and research into their optical properties].
L P Safonova et al.
Meditsinskaia tekhnika, (1)(1), 1-6 (2013-06-22)

Articles

In this article, we will discuss the benefits and limitations of several 2D and 3D scaffold patterning techniques that can be applied in the presence of cells. Although these methods will be discussed in the context of poly(ethylene glycol) (PEG)-based hydrogels, they can technically be applied to any optically transparent, photoactive substrate.

The use of hydrogel-based biomaterials for the delivery and recruitment of cells to promote tissue regeneration in the body is of growing interest. This article discussed the application of hydrogels in cell delivery and tissue regeneration.

In the past two decades, tissue engineering and regenerative medicine have become important interdisciplinary fields that span biology, chemistry, engineering, and medicine.

Progress in biotechnology fields such as tissue engineering and drug delivery is accompanied by an increasing demand for diverse functional biomaterials. One class of biomaterials that has been the subject of intense research interest is hydrogels, because they closely mimic the natural environment of cells, both chemically and physically and therefore can be used as support to grow cells. This article specifically discusses poly(ethylene glycol) (PEG) hydrogels, which are good for biological applications because they do not generally elicit an immune response. PEGs offer a readily available, easy to modify polymer for widespread use in hydrogel fabrication, including 2D and 3D scaffold for tissue culture. The degradable linkages also enable a variety of applications for release of therapeutic agents.

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