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740225

Sigma-Aldrich

25-Hydroxyvitamin D2 solution

50 μg/mL in ethanol, 98% (CP)

Synonym(s):

25-Hydroxycalciferol solution, 25-Hydroxyergocalciferol solution

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About This Item

Empirical Formula (Hill Notation):
C28H44O2
Molecular Weight:
412.65
EC Number:
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.24

Quality Level

assay

98% (CP)

form

solution

concentration

50 μg/mL in ethanol

technique(s)

mass spectrometry (MS): suitable

color

colorless

application(s)

detection

storage temp.

−20°C

SMILES string

C[C@H](\C=C\[C@H](C)C(C)(C)O)[C@H]1CC[C@H]2C(\CCC[C@]12C)=C\C=C3\C[C@@H](O)CCC3=C

InChI

1S/C28H44O2/c1-19-10-14-24(29)18-23(19)13-12-22-8-7-17-28(6)25(15-16-26(22)28)20(2)9-11-21(3)27(4,5)30/h9,11-13,20-21,24-26,29-30H,1,7-8,10,14-18H2,2-6H3/b11-9+,22-12+,23-13-/t20-,21+,24+,25-,26+,28-/m1/s1

InChI key

KJKIIUAXZGLUND-ICCVIKJNSA-N

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General description

25-Hydroxyvitamin D(ergocalciferol or 25-hydroxycalciferol) is a metabolite of vitamin D found in the liver. It is one of the most common forms of vitamin D circulating in the body and plays an important role in determining vitamin D deficiency.15}

Application

25-Hydroxyvitamin D2 can be used as an analytical standard for the quantitative analysis of 25-Hydroxyvitamin D2 content in biological fluids via LC-MS/MS.

Packaging

1 mL in ampule

pictograms

FlameExclamation mark

signalword

Danger

hcodes

Hazard Classifications

Eye Irrit. 2 - Flam. Liq. 2

wgk_germany

WGK 1

flash_point_f

57.2 °F

flash_point_c

14 °C


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Determinants of vitamin D deficiency from Sun exposure: a global perspective
Vitamin D, 19(1), 79-90 (2018)
Development and validation of an LC-MS/MS based method for quantification of 25 hydroxyvitamin D2 and 25 hydroxyvitamin D3 in human serum and plasma
Zhang SW, et al.
Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences, 961(1), 62-70 (2014)
Maarten W Taal et al.
Kidney international, 86(2), 407-413 (2014-01-17)
Fibroblast growth factor (FGF) 23 is an important regulator of phosphaturia. Its serum level was found to increase before that of parathyroid hormone (PTH) in early chronic kidney disease (CKD) in some but not all previous studies. As vitamin D
10 years of 25-hydroxyvitamin-D testing by LC-MS/MS-trends in vitamin-D deficiency and sufficiency
Galior K, et al.
Bone Reports, 8(1), 268-273 (2018)
Vitamin-D2 treatment-associated decrease in 25 (OH) D3 level is a reciprocal phenomenon: a randomized controlled trial
Hammami, MM et al.
BMC endocrine disorders, 19(1), 8-8 (2019)

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