Skip to Content
MilliporeSigma
All Photos(1)

Documents

75666

Sigma-Aldrich

5-(Benzylthio)-1H-tetrazole

≥99.0% (HPLC)

Synonym(s):

5-Benzylmercapto-1,2,3,4-tetrazole, 5-Benzylmercaptotetrazole, 5-Benzylthio-1H-tetrazole, 5-[(Phenylmethyl)thio]-2H-tetrazole

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

Empirical Formula (Hill Notation):
C8H8N4S
CAS Number:
21871-47-6
Molecular Weight:
192.24
MDL number:
MFCD00068731
UNSPSC Code:
12352100
PubChem Substance ID:
57652580
NACRES:
NA.22

Quality Level

100

assay

≥99.0% (HPLC)

form

crystals

mp

135-138 °C (DSC-onset)

SMILES string

C(Sc1nnn[nH]1)c2ccccc2

InChI

1S/C8H8N4S/c1-2-4-7(5-3-1)6-13-8-9-11-12-10-8/h1-5H,6H2,(H,9,10,11,12)

InChI key

GXGKKIPUFAHZIZ-UHFFFAOYSA-N

Related Categories

General description

5-(Benzylthio)-1H-tetrazole (BTT activator) is an organic compound that is used as an activator in the synthesis of oligonucleotides. The activator reacts with the phosphoramidite group to form a highly reactive intermediate. The intermediate then forms an internucleotide bond with the detritylated 5′-hydroxyl group of the growing oligonucleotide chain.

Other Notes

Activator for DNA synthesis; superior alternative to tetrazole

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Customers Also Viewed

Slide 1 of 4

1 of 4

Sigma-Aldrich

Sigma-Aldrich

L031100

Activator 42®

ETT Activator 0.25 M, configured for PerkinElmer, configured for Polygen, configured for MerMade, configured for ABI 3900

Sigma-Aldrich

L030080

ETT Activator

Sigma-Aldrich

Sigma-Aldrich

BI0424

Oxidizing Reagent, 0.05M, I₂ in Pyridine

Sigma-Aldrich

Sigma-Aldrich

555339

Cap Mix A, (80% Tetrahydrofuran, 10% Acetic Anhydride, 10% Pyridine)

S. Pitsch et al.
Helvetica Chimica Acta, 84, 3773-3773 (2001)

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service