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809608

Sigma-Aldrich

Biotin-2′,2′,3′,3′-d4

≥98 atom % D, ≥95% (CP)

Synonym(s):

Vitamin B7-d4, Vitamin B8-d4, Vitamin H-d4

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About This Item

Empirical Formula (Hill Notation):
C10D4H12N2O3S
Molecular Weight:
248.34
UNSPSC Code:
12352200
PubChem Substance ID:
329769172
NACRES:
NA.12

isotopic purity

≥98 atom % D

Quality Level

200

assay

≥95% (CP)

form

powder

technique(s)

mass spectrometry (MS): suitable

color

white to off-white

mp

228 °C

mass shift

M+4

storage temp.

−20°C

SMILES string

OC(CC([2H])([2H])C([2H])([2H])C[C@@H]1SC[C@@]2([H])[C@]1([H])NC(N2)=O)=O

InChI

1S/C10H16N2O3S/c13-8(14)4-2-1-3-7-9-6(5-16-7)11-10(15)12-9/h6-7,9H,1-5H2,(H,13,14)(H2,11,12,15)/t6-,7-,9-/m0/s1/i1D2,2D2

InChI key

YBJHBAHKTGYVGT-CCSQOTJNSA-N

Related Categories

General description

Biotin is a water-soluble vitamin B which is also known as vitamin B7. It is involved in the synthesis of fatty acids and gluconeogenesis. Biotin is found in plants and animals. Its deficiency causes retardation in growth, alopecia and neurological impairment in humans and animals.
Biotin-2′,2′,3′,3′-d4 is an isotope of vitamin B7 wherein C-2′, C-2′, C-3′, C-3′ protons are replaced by deuterium.

Application

Biotin-2′,2′,3′,3′-d4 can be used as a stable isotope internal standard for accurate data interpretation in specific biological samples.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Clinical biochemistry, 83, 78-80 (2020-05-31)
Despite the increasing awareness about biotin interference with immunoassays, so far, only two studies have quantified the prevalence of elevated biotin in patient populations. In a US study, over 7% had biotin concentrations exceeding 10 ng/mL, whereas in an Australian study
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