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855049

Sigma-Aldrich

5-Azacytosine

Synonym(s):

2-Hydroxy-4-aminotriazine, 4-Amino-1,3,5-triazin-2-ol, 4-Amino-1,3,5-triazin-2-one, 4-Amino-2-hydroxy-1,3,5-triazine, NSC 51100, NSC 54006

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About This Item

Empirical Formula (Hill Notation):
C3H4N4O
CAS Number:
Molecular Weight:
112.09
Beilstein/REAXYS Number:
116378
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

form

powder

Quality Level

mp

>300 °C (lit.)

SMILES string

NC1=NC(=O)NC=N1

InChI

1S/C3H4N4O/c4-2-5-1-6-3(8)7-2/h1H,(H3,4,5,6,7,8)

InChI key

MFEFTTYGMZOIKO-UHFFFAOYSA-N

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Application

Reactant for:
  • Enzymic synthesis of nucleoside analogs using immobilized 2′-deoxyribosyltransferase from Lactobacillus reuteri
  • Reactions with oxide radical ion

  • Potential antitumor and antiproliferative agent against human leukemia cells

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type N95 (US)


Certificates of Analysis (COA)

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AMB Express, 10(1), 173-173 (2020-09-30)
A novel IDA-LaNDT derivative was able to reach the highest productivity in the biosynthesis of a well-known antitumoral agent called decitabine. However, the combination of two simple and inexpensive techniques such as ionic absorption and gel entrapment with the incorporation

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