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861324

Sigma-Aldrich

p-Rosolic acid

Dye content 84 %

Synonym(s):

4-[Bis(4-hydroxyphenyl)methylene]-2,5-cyclohexadienone, Aurin

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About This Item

Empirical Formula (Hill Notation):
C19H14O3
CAS Number:
603-45-2
Molecular Weight:
290.31
Colour Index Number:
43800
Beilstein/REAXYS Number:
2055205
EC Number:
210-041-8
MDL number:
MFCD00001624
UNSPSC Code:
12171500
PubChem Substance ID:
24888536
NACRES:
NA.47

form

powder

Quality Level

200

composition

Dye content, 84%

technique(s)

titration: suitable

pH

5.0-6.8, yellow to pink

cation traces

C: 66.0-90.8%

λmax

482 nm

ε (extinction coefficient)

≥11000 at 264-270 nm in ethanol
≥50000 at 478-486 nm in ethanol

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

room temp

SMILES string

O=C(C=C1)C=CC1=C(C2=CC=C(O)C=C2)C3=CC=C(O)C=C3

InChI

1S/C19H14O3/c20-16-7-1-13(2-8-16)19(14-3-9-17(21)10-4-14)15-5-11-18(22)12-6-15/h1-12,20-21H

InChI key

FYEHYMARPSSOBO-UHFFFAOYSA-N

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General description

p-Rosolic acid (C.I. 43800) is an acid-baseindicator from the triphenylmethane group. It is also known as aurin and 4-[Bis(4-hydroxyphenyl)methylene]-2,5-cyclohexadienone.

Application

p-Rosolic acid has been used to induce cellular stress in HEK293 cells.

Biochem/physiol Actions

The transition range of p-Rosolic acid is around pH 6.6-8.0 (Below this pH range it is yellow and above it red).

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Simultaneous detection of the subcellular localization of RNAs and proteins in cultured cells by combined multicolor RNA-FISH and IF.
Meyer C, et al.
Methods, S1046-2023 (2016)
W O Grabow et al.
Applied and environmental microbiology, 42(2), 192-199 (1981-08-01)
MacConkey agar, standard M-FC agar, M-FC agar without rosolic acid, M-FC agar with a resuscitation top layer, Teepol agar, and pads saturated with Teepol broth, were evaluated as growth media for membrane filtration counting of fecal coliform bacteria in water.
Rakesh K Sharma et al.
Journal of medicinal chemistry, 49(12), 3595-3601 (2006-06-09)
Previously, we have reported that aurintricarboxylic acid (ATA) is one of the most potent inhibitors of the DNA binding of transcription factor NF-kappaB. We now report the NF-kappaB-DNA binding inhibitory activity of ATA analogues. An electrophoretic mobility shift assay has
[Not Available].
M MERINO SIMON et al.
Galicia-clinica, 18(12), 741-743 (1946-12-01)
Comparative bacteriostatic assays with rosaniline and its phenolic analog (rosolic acid).
E FISCHER et al.
Journal of bacteriology, 53(4), 381-388 (1947-04-01)
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