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Sigma-Aldrich

Fmoc-Dab(Boc)-OH

≥97.0% (HPLC)

Synonym(s):

Nα-Fmoc-Nγ-Boc-L-2,4-diaminobutyric acid

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About This Item

Empirical Formula (Hill Notation):
C24H28N2O6
CAS Number:
Molecular Weight:
440.49
Beilstein/REAXYS Number:
6250328
MDL number:
UNSPSC Code:
12352209
eCl@ss:
32160406
PubChem Substance ID:
NACRES:
NA.26

Quality Level

assay

≥97.0% (HPLC)

form

powder

optical activity

[α]20/546 −14.5±1°, c = 1% in methanol

reaction suitability

reaction type: Fmoc solid-phase peptide synthesis

application(s)

peptide synthesis

functional group

Boc
Fmoc

storage temp.

2-8°C

SMILES string

CC(C)(C)OC(=O)NCC[C@H](NC(=O)OCC1c2ccccc2-c3ccccc13)C(O)=O

InChI

1S/C24H28N2O6/c1-24(2,3)32-22(29)25-13-12-20(21(27)28)26-23(30)31-14-19-17-10-6-4-8-15(17)16-9-5-7-11-18(16)19/h4-11,19-20H,12-14H2,1-3H3,(H,25,29)(H,26,30)(H,27,28)/t20-/m0/s1

InChI key

LIWKOFAHRLBNMG-FQEVSTJZSA-N

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


Certificates of Analysis (COA)

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Ronald Domalaon et al.
Amino acids, 46(11), 2517-2530 (2014-07-30)
Taking a minimalistic approach in efforts to lower the cost for the development of new synthetic antimicrobial peptides, ultrashort cationic lipopeptides were designed to mimic the amphiphilic nature crucial for their activity but with only a very short peptide sequence
Kuo-Yuan Hung et al.
European journal of medicinal chemistry, 136, 154-164 (2017-05-12)
The 20-residue linear peptide A20FMDV2 has been shown to exhibit high selectivity and affinity for the tumour-related αvβ6 integrin and has potential as a vector for therapeutic drugs. However, it exhibits poor half-life in plasma in part due to its
Tony Velkov et al.
Cell chemical biology, 25(4), 380-391 (2018-02-06)
Resistance to the last-resort antibiotic colistin is now widespread and new therapeutics are urgently required. We report the first in toto chemical synthesis and pre-clinical evaluation of octapeptins, a class of lipopeptides structurally related to colistin. The octapeptin biosynthetic cluster consisted

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