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901021

Sigma-Aldrich

Poly(L-lactide-co-glycolide)

10:90, viscosity 1.7 dL/g 

Synonym(s):

PLGA

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About This Item

Linear Formula:
(C4H4O4)m(C6H8O4)n
UNSPSC Code:
12162002
NACRES:
NA.25

Quality Level

100

form

chips

feed ratio

lactide:glycolide 10:90±5

color

light yellow to tan

viscosity

1.4-2.0 dL/g
1.7 dL/g

shipped in

dry ice

storage temp.

−20°C

Related Categories

General description

Poly(L-lactide-co-glycolide) (PLGA) is a biodegradable and biocompatible copolymer synthesized from the ring opening polymerization of lactide and glycolide. Due to the ester linkages found in the polymer backbone, these polymers are able to degrade via hydrolysis. Depending on the ratio of monomers used and polymer block structure, different forms of PLGA can be obtained. These differing forms yield materials with different degrees of crystallinity, thermal transitions, solubility, and rates of degradation.

Application

Poly(L-lactide-co-glycolide) (PLGA) is a biodegradable and biocompatible copolymer for use in biomedical research devices, such as grafts, sutures, implants, prosthetic devices, surgical sealant films, scaffolds for tissue engineering applications, micro and nanoparticles. PLGA is also utilized in drug delivery research, such as in the synthesis and application of polymer-drug conjugates.

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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