901941
Thiol poly(ethylene glycol)-block-poly(lactide-co-glycolide)
PEG average Mn 5,000, PLGA average Mn 15,000, lactide:glycolide 50:50
Synonym(s):
Thiol-PEG-b-PLGA, Thiol-PEG-PLGA
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About This Item
Linear Formula:
C3H7SO(C2H4O)nC2H4O[(C2H2O2)x(C3H4O2)y]m
UNSPSC Code:
51171641
NACRES:
NA.23
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description
Identity: Conforms to structure
form
powder
feed ratio
lactide:glycolide 50:50
lactide:glycolide 50:50±5 (by NMR)
mol wt
PEG Mn 4000-6000 g/mol (by NMR)
PEG average Mn 5,000
PLGA Mn 13500-16500 g/mol (by NMR)
PLGA average Mn 15,000
color
white
storage temp.
−20°C
Related Categories
Application
Thiol poly(ethylene glycol)-block-poly(lactide-co-glycolide) is a thiol-functionalized, biocompatible, amphiphilic block copolymer. Due to its self-assembling properties, this material can be used in the formation of nanoparticles for drug delivery. Additionally, due to the thiol-functionalization of the PEG block, this material can be used to rapidly covalently conjugate biomolecules, API, or targeting ligands. Potential uses include the targeted and/or controlled release of cancer drugs, anti-inflammatory drugs, antibiotics, or anaesthetic agents.
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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