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905577

Sigma-Aldrich

Gold nanospheres

15 nm, Cy3 and biotin functionalized, powder

Synonym(s):

Cy3 labeled gold nanospheres, Cy3 tagged gold nanospheres, Dye labeled gold nanoparticles, Fluorescent labeled gold nanoparticles

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About This Item

UNSPSC Code:
12162002
NACRES:
NA.23

form

nanospheres
powder

particle size

15 nm

λmax

554 nm

storage temp.

2-8°C

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Application

Owing to size and shape dependent quantum effects, the gold nanoparticles exhibit unique surface plasmon resonance absorption, scattering, fluorescence, and photothermal properties which render them suitable for applications in catalysis, chemical sensing, biosensing, cellular and bioimaging, drug and gene delivery, and photothermal therapy. The fluorescent labeling of gold nanoparticles have been shown to cause emission enhancement in fluorophores. This makes the fluorescence tagged gold nanoparticles a dual mode nanoprobe for drug delivery and bioimaging applications.

Legal Information

Product of Nanopartz Inc.

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H317

Hazard Classifications

Skin Sens. 1

wgk_germany

WGK 1

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Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Fluorescently Labeled Gold Nanoparticles with Minimal Fluorescence Quenching.
Lu Y, et al.
The Journal of Physical Chemistry C, 114, 17446-17446 (2010)
Nuri Oh et al.
ACS nano, 8(6), 6232-6241 (2014-05-20)
Significant quantities of synthetic nanoparticles circulating in the body are cleared and retained for long periods of time in the resident macrophages of the mononuclear phagocytic system (MPS), increasing the likelihood of nanoparticle-mediated chronic toxicity. To date, there has been
Xiaohua Huang et al.
Journal of the American Chemical Society, 128(6), 2115-2120 (2006-02-09)
Due to strong electric fields at the surface, the absorption and scattering of electromagnetic radiation by noble metal nanoparticles are strongly enhanced. These unique properties provide the potential of designing novel optically active reagents for simultaneous molecular imaging and photothermal
Gold nanoparticles in chemical and biological sensing.
Krishnendu Saha et al.
Chemical reviews, 112(5), 2739-2779 (2012-02-03)
Susie Eustis et al.
Chemical Society reviews, 35(3), 209-217 (2006-03-01)
This tutorial review presents an introduction to the field of noble metal nanoparticles and their current applications. The origin of the surface plasmon resonance and synthesis procedures are described. A number of applications are presented that take advantage of the
View All Related Papers

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Recent Progress on Nonviral Delivery Carriers for CRISPR/Cas9 Systems

The CRISPR/Cas9 system has recently emerged as a highly specific, efficient, and versatile gene editing technology that can be utilized to build disease models and correct diseased genes. Safe and effective delivery vectors for the CRISPR/Cas9 system are in critical need to enable clinical development and future applications of CRISPR/Cas9 systems. Professor Yang Liu summarizes recent progress in nonviral nanoparticle approaches for CRISPR/Cas9 delivery.

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