Skip to Content
MilliporeSigma
All Photos(2)

Documents

910813

Sigma-Aldrich

mPEG24-NHS

Synonym(s):

Methoxypolyethylene glycol acetic acid N-succinimidyl ester, mPEG NHS

Sign Into View Organizational & Contract Pricing
All Photos(2)

About This Item

Empirical Formula (Hill Notation):
C56H107NO29
CAS Number:
174569-25-6
Molecular Weight:
1258.44
MDL number:
MFCD28385538
UNSPSC Code:
43211915

assay

95% (HPLC)

form

solid

mol wt

average Mn 1,250 (by NMR)

reaction suitability

reagent type: chemical modification reagent
reactivity: amine reactive

color

white to off-white

Ω-end

NHS ester

α-end

methoxy

polymer architecture

shape: linear
functionality: monofunctional

storage temp.

−20°C

Related Categories

Application

Polyethylene glycols (PEGs) are FDA approved hydrophilic polymers. They are non-toxic, non-immunogenic and non-antigenic, and are widely used in a variety of biomedical applications such as bioconjugation, drug delivery, surface functionalization, and tissue engineering. PEG-NHS is an amine reactive PEG that can react to amino groups of lysine(s) on proteins or other biologics; reaction occurs at room temperature in <1hr at pH 7-8. Stable linker between PEG and NHS ester.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

230.0 °F

flash_point_c

> 110 °C

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Articles

Recent Progress on Nonviral Delivery Carriers for CRISPR/Cas9 Systems

The CRISPR/Cas9 system has recently emerged as a highly specific, efficient, and versatile gene editing technology that can be utilized to build disease models and correct diseased genes. Safe and effective delivery vectors for the CRISPR/Cas9 system are in critical need to enable clinical development and future applications of CRISPR/Cas9 systems. Professor Yang Liu summarizes recent progress in nonviral nanoparticle approaches for CRISPR/Cas9 delivery.

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service