918962
Poly(ethylene glycol) methyl ether-block-poly(D,L lactide)
PEG average Mn 5000, PDLA average Mn 50000
Synonym(s):
Biodegradable, Block copolymer, Drug delivery, PEG-PLA, PLLA, mPEG-PLA, mPEG-PLLA
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About This Item
Linear Formula:
HO[CH(CH3)COO]m[CH2CH2O]nCH3
UNSPSC Code:
12352106
NACRES:
NA.23
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form
solid
Quality Level
mol wt
PDLA average Mn 50,000 (by NMR)
PDLA average Mn 50000
PEG average Mn 5,000 (by NMR)
PEG average Mn 5000
color
white to yellow
storage temp.
2-8°C
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Application
Poly(ethylene glycol) methyl ether-block-poly(D,L lactide) is an amphiphilic, diblock copolymer composed of a hydrophilic PEG block and a hydrophobic PLA block. These biodegradable, biocompatible polymers can self-assemble to form nanoparticles, such as micelles and polymersomes, in both aqueous and non-aqueous media. Due to these properties, these polymers are widely used in polymeric nanoparticle formulation to achieve controlled and targeted delivery of therapeutic agents (e.g. APIs, genetic material, peptides, vaccines, and antibiotics).
wgk_germany
WGK 3
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