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927457

Sigma-Aldrich

SDASO-S crosslinker

≥95%

Synonym(s):

2,5-Dioxopyrrolidin-1-yl 3-((2-(3-methyl-3H-diazirin-3-yl)ethyl)sulfinyl)propanoate, Succinimidyl diazirine sulfoxide

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About This Item

Empirical Formula (Hill Notation):
C11H15N3O5S
Molecular Weight:
301.32
UNSPSC Code:
12352106

Quality Level

assay

≥95%

form

powder

mp

87 °C

storage temp.

−20°C

SMILES string

O=C(CCS(CCC1(N=N1)C)=O)ON2C(CCC2=O)=O

Application

SDASO-S (succinimidyl diazirine sulfoxide) is mass-spectrometry cleavable heterobifunctional cross-linker, which can be used in the analysis of protein structure, or protein-protein interactions. SDASO-S is photoactivated, allowing for the first time photocross-linking of proteins, and rapid, accurate analysis by MS.

Product can be used with our line of photoreactors: Including Penn PhD (Z744035) & SynLED 2.0 (Z744080)

Other Notes

https://www.sciencedirect.com/science/article/pii/S1535947621000578">Enabling Photoactivated Cross-Linking Mass Spectrometric Analysis of Protein Complexes by Novel MS-Cleavable Cross-Linkers

pictograms

Flame

signalword

Danger

hcodes

Hazard Classifications

Self-react. C

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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