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W518905

Sigma-Aldrich

Sodium propionate

FCC

Synonym(s):

Propionic acid sodium salt

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About This Item

Linear Formula:
CH3CH2COONa
CAS Number:
137-40-6
Molecular Weight:
96.06
Beilstein/REAXYS Number:
3566934
EC Number:
205-290-4
MDL number:
MFCD00002759
UNSPSC Code:
12164502
PubChem Substance ID:
24902079
NACRES:
NA.21

biological source

synthetic

Quality Level

400

grade

Halal
Kosher

reg. compliance

FCC
FDA 21 CFR 150.141
FDA 21 CFR 150.161
FDA 21 CFR 179.45
FDA 21 CFR 180.23
FDA 21 CFR 184.1784

assay

99%

mp

285-286 °C (lit.)

solubility

H2O: 10%, clear, colorless

application(s)

flavors and fragrances

documentation

see Safety & Documentation for available documents

food allergen

no known allergens

organoleptic

faint

SMILES string

[Na+].CCC([O-])=O

InChI

1S/C3H6O2.Na/c1-2-3(4)5;/h2H2,1H3,(H,4,5);/q;+1/p-1

InChI key

JXKPEJDQGNYQSM-UHFFFAOYSA-M

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General description

Dipentene is one of the flavor constituents of spearmint oil. It used in toothpaste and electronic cigarettes.
Sodium propionate is generally used as a preservative in bread due to its anti-microbial and anti-mycotic properties.

Application


  • The Effects of Short-Chain Fatty Acids in Gut Immune and Oxidative Responses of European Sea Bass (Dicentrarchus labrax): An Ex Vivo Approach.: This study examines the beneficial effects of sodium propionate on gut health and immune responses in European sea bass, highlighting its potential as a dietary supplement to enhance fish health and disease resistance (Fontinha F et al., 2024).

  • Melatonin protects zebrafish pancreatic development and physiological rhythms from sodium propionate-induced disturbances via the hypothalamic-pituitary-thyroid axis.: Research investigates how sodium propionate impacts endocrine functions in zebrafish, suggesting its broader implications in endocrinology and toxicology studies (Xu Y et al., 2024).

Disclaimer

For R&D or non-EU Food use. Not for retail sale.

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Comparative analysis of the antimicrobial activity of cinnamon oil and cinnamon extract on some food-borne microbes.
Gupta C, et al.
African Journal of Microbiology Research, 2(9), 247-251 (2008)
Contact allergy to toothpaste flavors.
Andersen KE.
Contact Dermatitis, 4(4), 195-198 (1978)
Effect of Flavoring Chemicals on Free Radical Formation in Electronic Cigarette Aerosols.
Bitzer ZT, et al.
Free Radical Biology & Medicine, 112, 200-200 (2017)
Evaluation of genotoxic effects of sodium propionate, calcium propionate and potassium propionate on the root meristem cells of Allium cepa.
Turko?lu S.
Food And Chemical Toxicology, 46(6), 2035-2041 (2008)
Bistra B Nankova et al.
PloS one, 9(8), e103740-e103740 (2014-08-30)
Alterations in gut microbiome composition have an emerging role in health and disease including brain function and behavior. Short chain fatty acids (SCFA) like propionic (PPA), and butyric acid (BA), which are present in diet and are fermentation products of
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