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850355P

Avanti

16:0 PC (DPPC)

Name: 16:0 PC (DPPC)
Brand: AVANTI

Avanti Polar Lipids

Synonym(s):

1,2-dihexadecanoyl-sn-glycero-3-phosphocholine; DPPC; PC(16:0/16:0)

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About This Item

Empirical Formula (Hill Notation):

C₄₀H₈₀NO₈P

CAS Number:

63-89-8

Molecular Weight:

734.04

UNSPSC Code:

51191904

NACRES:

NA.25

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Sigma-Aldrich

P4329

1,2-Dipalmitoyl-sn-glycero-3-phosphocholine

Sigma-Aldrich

P0763

1,2-Dipalmitoyl-sn-glycero-3-phosphocholine

Sigma-Aldrich

C8667

Cholesterol

Sigma-Aldrich

P6636

L-α-Phosphatidylinositol from Glycine max (soybean)

Sigma-Aldrich

P3556

L-α-Phosphatidylcholine

description

1,2-dipalmitoyl-sn-glycero-3-phosphocholine

assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 1 g (850355P-1g)
pkg of 1 × 200 mg (850355P-200mg)
pkg of 1 × 25 mg (850355P-25mg)
pkg of 1 × 500 mg (850355P-500mg)

manufacturer/tradename

Avanti Polar Lipids

lipid type

phospholipids
cardiolipins

shipped in

dry ice

storage temp.

−20°C

SMILES string

[O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(CCCCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCCCC)=O)=O

InChI

1S/C40H80NO8P/c1-6-8-10-12-14-16-18-20-22-24-26-28-30-32-39(42)46-36-38(37-48-50(44,45)47-35-34-41(3,4)5)49-40(43)33-31-29-27-25-23-21-19-17-15-13-11-9-7-2/h38H,6-37H2,1-5H3

InChI key

KILNVBDSWZSGLL-UHFFFAOYSA-N

General description

1,2-dihexadecanoyl-sn-glycero-3-phosphocholine (DPPC) is synthesized from unsaturated phosphatidylcholine (PC) by direct de novo synthesis via α1,2-dipalmitoyl diacylglycerol intermediate. The enzyme cholinephosphotransferase catalyzes the conversion of 1,2-dipalmitoyl diacylglycerol to DPPC. Synthesis of DPPC also occurs via remodeling pathway involving deacylation of unsaturated PC.

The list of Phosphatidylcholine products offered by Avanti is designed to provide compounds having a variety of physical properties. Products available include short chain (C3-C8 are water soluble and hygroscopic), saturated, multi-unsaturated and mixed acid PC′s. All of the products are purified by HPLC, and special precautions are taken to protect the products for oxidization and hydrolysis.

Application

16:0 PC (DPPC) has been used in the generation of thymoquinone (TQ) liposomes, gold nanorods and calcium chloride encapsulated liposomes and bilayers for biophysical studies.

Biochem/physiol Actions

1,2-dihexadecanoyl-sn-glycero-3-phosphocholine (DPPC) is a surfactant and reduces surface tension. It is used in combination with 1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC) for lipid bilayer generation. DPPC alone and in combination with other phospholipid is effective in drug encapsulation and delivery.

Packaging

20 mL Clear Glass Screw Cap Vial (850355P-1g)

20 mL Clear Glass Screw Cap Vial (850355P-500mg)

5 mL Amber Glass Screw Cap Vial (850355P-200mg)

5 mL Amber Glass Screw Cap Vial (850355P-25mg)

also commonly purchased with this product

Product No.

Description

Pricing

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Phenotypic basis for matrix stiffness-dependent chemoresistance of breast cancer cells to doxorubicin

Joyce MH, et al.

Frontiers in Oncology, 8, 203-208 (2018)

Identification and characterization of a lysophosphatidylcholine acyltransferase in alveolar type II cells

Chen X, et al.

Proceedings of the National Academy of Sciences of the USA, 103(31), 11724-11729 (2006)

Calcium and Zinc Differentially Affect the Structure of Lipid Membranes.

Norbert Kučerka et al.

Langmuir : the ACS journal of surfaces and colloids, 33(12), 3134-3141 (2017-03-10)

Interactions of calcium (Ca2+) and zinc (Zn2+) cations with biomimetic membranes made of dipalmitoylphosphatidylcholine (DPPC) were studied by small angle neutron diffraction (SAND). Experiments show that the structure of these lipid bilayers is differentially affected by the two divalent cations.

The effect of temperature on supported dipalmitoylphosphatidylcholine (DPPC) bilayers: structure and lubrication performance.

Min Wang et al.

Journal of colloid and interface science, 445, 84-92 (2015-01-18)

Phospholipids fulfill an important role in joint lubrication. They, together with hyaluronan and glycoproteins, are the biolubricants that sustain low friction between cartilage surfaces bathed in synovial fluid. In this work we have investigated how the friction force and load

Formation of nanopores in DiynePC-DPPC complex lipid bilayers triggered by on-demand photo-polymerization

Chun MJ, et al.

Royal Society of Chemistry Advances, 8(49), 27988-27994 (2018)

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Documents

16:0 PC (DPPC)

Avanti Polar Lipids

About This Item

Recommended Products

Properties

description

assay

form

packaging

manufacturer/tradename

lipid type

shipped in

storage temp.

SMILES string

InChI

InChI key

Description

General description

Application

Biochem/physiol Actions

Packaging

Related Products

also commonly purchased with this product

Safety Information

Storage Class

wgk_germany

flash_point_f

flash_point_c

Documentation

Certificates of Analysis (COA)

Already Own This Product?

Peer Reviewed Papers

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