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6-Acetylmorphine-d3 solution

100 μg/mL in acetonitrile, ampule of 1 mL, certified reference material, Cerilliant®

Synonym(s):

6-Acetylmorphine-N-methyl-d3 solution

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About This Item

Empirical Formula (Hill Notation):
C19D3H18NO4
CAS Number:
Molecular Weight:
330.39
EC Number:
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24

grade

certified reference material

Quality Level

form

liquid

feature

SNAP-N-SPIKE®. SNAP-N-SHOOT®

packaging

ampule of 1 mL

manufacturer/tradename

Cerilliant®

drug control

Narcotic Licence Schedule A (Switzerland); estupefaciente (Spain); Decreto Lei 15/93: Tabela IA (Portugal)

concentration

100 μg/mL in acetonitrile

technique(s)

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

application(s)

forensics and toxicology

format

single component solution

mass shift

M+3

storage temp.

−20°C

SMILES string

[2H]C([2H])([2H])N1CC[C@]23C4Oc5c(O)ccc(CC1C2C=C[C@@H]4OC(C)=O)c35

InChI

1S/C19H21NO4/c1-10(21)23-15-6-4-12-13-9-11-3-5-14(22)17-16(11)19(12,18(15)24-17)7-8-20(13)2/h3-6,12-13,15,18,22H,7-9H2,1-2H3/t12-,13+,15-,18-,19-/m0/s1/i2D3

InChI key

JJGYGPZNTOPXGV-VALGNVEGSA-N

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General description

A stable-labeled internal standard suitable for quantitation of 6-acetylmorphine (6-MAM) levels in GC/MS or LC/MS testing for clinical toxicology, forensic analysis, urine drug testing, pain prescription monitoring and isotope dilution methods. Also known as 6-monoacetylmorphine, 6-MAM is an active metabolite of heroin and biomaker of heroin usage.

Application


  • Quantitative analysis of opiates in human fluids: A study employed 6-Acetylmorphine-d3 solution as part of a bioanalytical method using gas chromatography-triple quadrupole mass spectrometry for the precise quantification of opiates in human blood samples, highlighting its utility in forensic and clinical toxicology (Saad et al., 2019).

  • Enhanced opioid metabolite detection: Research integrated 6-Acetylmorphine-d3 solution in an electrospray LC-MS method with solid-phase extraction, significantly improving the accuracy of detecting opioid metabolites in urine. This method is vital for drug monitoring and pharmacokinetic studies (Svensson et al., 2007).

  • Forensic application in controlled drug programs: A study used 6-Acetylmorphine-d3 solution to establish dose-concentration relationships in hair from subjects in a controlled heroin-maintenance program, proving its essential role in forensic science for monitoring drug intake (Kintz et al., 1998).

  • Drug monitoring in clinical settings: The solution was also applied in a novel assay for the determination of opioids in blood and pericardial fluid, offering a robust tool for clinical diagnostics and forensic investigations (Ferreira et al., 2020).

Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

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pictograms

FlameExclamation mark

signalword

Danger

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2

wgk_germany

WGK 2

flash_point_f

35.6 °F

flash_point_c

2 °C


Certificates of Analysis (COA)

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