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D-910

Supelco

Diazepam-d5 solution

1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

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About This Item

Empirical Formula (Hill Notation):
C16D5H8ClN2O
CAS Number:
65854-76-4
Molecular Weight:
289.77
EC Number:
200-659-6
MDL number:
MFCD00070151
UNSPSC Code:
41116107
PubChem Substance ID:
329798892
NACRES:
NA.24

grade

certified reference material

Quality Level

300

form

liquid

feature

Snap-N-Spike®/Snap-N-Shoot®

packaging

ampule of 1 mL

manufacturer/tradename

Cerilliant®

drug control

Narcotic Licence Schedule B (Switzerland); psicótropo (Spain); Decreto Lei 15/93: Tabela IV (Portugal)

concentration

1.0 mg/mL in methanol

technique(s)

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

application(s)

clinical testing

format

single component solution

storage temp.

−20°C

SMILES string

O=C1CN=C(C2=C([2H])C([2H])=C([2H])C([2H])=C2[2H])C3=C(C=CC(Cl)=C3)N1C

InChI

1S/C16H13ClN2O/c1-19-14-8-7-12(17)9-13(14)16(18-10-15(19)20)11-5-3-2-4-6-11/h2-9H,10H2,1H3/i2D,3D,4D,5D,6D

InChI key

AAOVKJBEBIDNHE-VIQYUKPQSA-N

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General description

Diazepam is a benzodiazepine used to treat a number of symptoms from anxiety and panic attacks to insomnia. This stable-labeled internal standard is suited for quantitation of diazepam levels in urine, serum, or plasma by LC/MS or GC/MS for urine drug testing, clinical toxicology, forensic analysis, or isotope dilution methods. Diazepam, a benzodiazpine frequently abused recreationally, is sold under the trade name Valium®.

Application


  • Diazepam-d₅ as an analytical standard: Diazepam-d₅ is widely used as a stable isotope-labeled standard in analytical research for accurate quantification of diazepam in biological samples. It ensures high precision in mass spectrometry analyses, crucial for both therapeutic monitoring and forensic investigations (Wagmann et al., 2020).

  • Internal standard in mass spectrometry: As an internal standard, Diazepam-d₅ provides consistency and accuracy in mass spectrometric quantification of drugs, aiding in the robust analysis required in pharmacokinetic studies and drug metabolism research. This application is essential for determining drug concentration and studying metabolic pathways in clinical pharmacology (Villain et al., 2004).

Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany
Valium is a registered trademark of Roche Products Inc.

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signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

target_organs

Eyes

Storage Class

3 - Flammable liquids

wgk_germany

WGK 2

flash_point_f

49.5 °F - closed cup

flash_point_c

9.7 °C - closed cup

Certificates of Analysis (COA)

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