06-127
Anti-PDGF Antibody, neutralizing
Upstate®, from goat
Synonym(s):
Anti-PDGF-A, Anti-PDGF1
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About This Item
UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41
Recommended Products
biological source
goat
Quality Level
antibody form
purified antibody
antibody product type
primary antibodies
clone
polyclonal
species reactivity
bovine, pig, mouse, human
manufacturer/tradename
Upstate®
technique(s)
western blot: suitable
isotype
IgG
shipped in
dry ice
target post-translational modification
unmodified
Gene Information
human ... PDGFA(5154)
Immunogen
Purified human PDGF-AB; recognizes PDGF AA, AB and BB.
Application
Anti-PDGF Antibody, neutralizing detects level of PDGF & has been published & validated for use in WB.
Research Category
Signaling
Signaling
Research Sub Category
Growth Factors & Receptors
Growth Factors & Receptors
Target description
14/16 kDa
Physical form
DEAE chromatography
Format: Purified
Legal Information
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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wgk_germany
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Coagulation factor Xa stimulates platelet-derived growth factor release and mitogenesis in cultured vascular smooth muscle cells of rat
Ko, F. N., et al
The Journal of Clinical Investigation, 98, 1493-1501 (1996)
Polypeptide growth factors: roles in normal and abnormal cell growth.
Deuel, T F
Annual Review of Cell Biology, 3, 443-492 (1987)
A Görlach et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 14(11), 1518-1528 (2000-08-06)
Vascular injury after balloon angioplasty results in the rapid activation of platelets leading to the release of growth factors and vasoactive substances. In addition, up-regulation of tissue factor (TF) and an increased production of reactive oxygen species (ROS) have been
Thomas V Johnson et al.
Brain : a journal of neurology, 137(Pt 2), 503-519 (2013-11-02)
The development of neuroprotective strategies to attenuate retinal ganglion cell death could lead to novel therapies for chronic optic neuropathies such as glaucoma. Intravitreal transplantation of mesenchymal stem cells slows retinal ganglion cell death in models of optic nerve injury
Platelet-derived growth factor receptor regulates salivary gland morphogenesis via fibroblast growth factor expression.
Shinya Yamamoto,Emiko Fukumoto,Keigo Yoshizaki,Tsutomu Iwamoto,Aya Yamada,Kojiro Tanaka et al.
The Journal of Biological Chemistry null
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