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07-280

Sigma-Aldrich

Anti-PEDF Antibody

Upstate®, from rabbit

Synonym(s):

Anti-EPC-1, Anti-OI6, Anti-PEDF, Anti-PIG35

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

rabbit

Quality Level

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

polyclonal

species reactivity

human, mouse

manufacturer/tradename

Upstate®

technique(s)

western blot: suitable

isotype

IgG

NCBI accession no.

UniProt accession no.

shipped in

dry ice

target post-translational modification

unmodified

Gene Information

human ... SERPINF1(5176)

Specificity

PEDF

Immunogen

His tagged fusion protein corresponding to full length human PEDF (Pigment Epitheliuml Derived Factor) expressed in baby hamster kidney cells

Application

Anti-PEDF Antibody is an antibody against PEDF for use in WB.
Research Category
Neuroscience
Research Sub Category
Neurochemistry & Neurotrophins

Quality

routinely evaluated by immunoblot on RIPA lysates from Y79 cells

Target description

50kDa

Physical form

0.1M Tris-glycine, pH 7.4, 0.15M NaCl, 0.05% sodium azide before the addition of glycerol to 30%
Format: Purified
Protein A chromatography

Storage and Stability

2 years at -20°C

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Fei Zhang et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 27(9), 3730-3740 (2013-06-05)
Tissue perivascular resident macrophages (PVM/Ms), a hybrid cell type with characteristics of both macrophages and melanocytes, are critical for establishing and maintaining the endocochlear potential (EP) required for hearing. The PVM/Ms modulate expression of tight- and adherens-junction proteins in the
Huixia Lu et al.
Frontiers in pharmacology, 8, 783-783 (2017-11-29)
Angiogenesis is the formation of new blood vessels from the existing vasculature, which is involved in multiple biological processes, including atherosclerosis, ischemic heart disease, and cancer. Ginsenoside-Rb1 (Rb1), the most abundant ginsenoside isolated form Panax ginseng, has been identified as
Pigment epithelium-derived factor (PEDF) protects cortical neurons in vitro from oxidant injury by activation of extracellular signal-regulated kinase (ERK) 1/2 and induction of Bcl-2.
Sanchez, A; Tripathy, D; Yin, X; Luo, J; Martinez, J; Grammas, P
Neuroscience Research null
Alma Sanchez et al.
Neuropeptides, 44(4), 323-331 (2010-05-01)
A large literature demonstrates the multifunctional nature of vascular endothelial growth factor (VEGF). Though initially characterized as an endothelial cell-specific factor, recent studies reveal that VEGF has numerous effects on diverse cell types in the brain including neurons. The objective
P C Karakousis et al.
Molecular vision, 7, 154-163 (2001-07-05)
To localize pigment epithelium-derived factor (PEDF) in developing and adult human ocular tissues. PEDF was localized in fetal and adult eyes by immunofluorescence with a polyclonal antibody (pAb) against amino acids 327-343 of PEDF, or a monoclonal antibody (mAb) against

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