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1.00514

Supelco

Perchloric acid

70%, for analysis (max. 0.0000005% Hg) EMSURE® ACS,ISO,Reag. Ph Eur

Synonym(s):

Perchloric acid, PCA

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About This Item

Linear Formula:
HClO4
CAS Number:
Molecular Weight:
100.46
MDL number:
UNSPSC Code:
12352301
NACRES:
NA.21

product name

Perchloric acid 70%, for analysis (max. 0.0000005% Hg) EMSURE® ACS,ISO,Reag. Ph Eur

grade

ACS reagent

Quality Level

agency

reag. ISO
reag. Ph. Eur.

product line

EMSURE®

form

liquid

concentration

70.0-72.0% HClO4

impurities

≤0.005 ppm Hg (Mercury)
≤0.02 ppm Ba (Barium)
≤0.02 ppm Be (Beryllium)
≤0.02 ppm Li (Lithium)
≤0.02 ppm Mn (Manganese)
≤0.02 ppm Sr (Strontium)
≤0.05 ppm Al (Aluminium)
≤0.05 ppm As (Arsenic)
≤0.05 ppm Cd (Cadmium)
≤0.05 ppm Co (Cobalt)
≤0.05 ppm Ge (Germanium)
≤0.05 ppm Mo (Molybdenum)
≤0.05 ppm Pb (Lead)
≤0.05 ppm Tl (Thallium)
≤0.05 ppm V (Vanadium)
≤0.1 ppm Ag (Silver)
≤0.1 ppm Bi (Bismuth)
≤0.1 ppm Cu (Copper)
≤0.1 ppm K (Potassium)
≤0.1 ppm Ni (Nickel)
≤0.1 ppm Ti (Titanium)
≤0.1 ppm Zn (Zinc)
≤0.1 ppm Zr (Zirconium)
≤0.5 ppm Ca (Calcium)
≤0.5 ppm Free chlorine
≤0.5 ppm Mg (Magnesium)
≤0.5 ppm Na (Sodium)
≤1 ppm Heavy metals (as Pb)
≤1.0 ppm Fe (Iron)
≤10 ppm Chlorate (ClO3)
≤10 ppm Sulfate (SO4)
≤10 ppm Total nitrogen (N)
≤3 ppm Chloride (Cl)
≤5 ppm Phosphate and Silicate (as SiO2)

ign. residue

≤30 ppm (as sulfate)

SMILES string

OCl(=O)(=O)=O

color

APHA: ≤10

bp

198.7 °C/1013 hPa

mp

-18 °C

density

1.68 g/cm3 at 20 °C

storage temp.

15-25°C

InChI

1S/ClHO4/c2-1(3,4)5/h(H,2,3,4,5)

InChI key

VLTRZXGMWDSKGL-UHFFFAOYSA-N

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Application

  • Development and validation of an HPLC method for the determination of vancomycin in human plasma and its comparison with an immunoassay (PETINIA).: This study developed and validated an HPLC method using 70% perchloric acid for the determination of vancomycin in human plasma, highlighting its application in analytical chemistry for therapeutic drug monitoring (Usman and Hempel, 2016).
  • Determination of sunscreen agents in cosmetic products by reversed-phase high performance liquid chromatography.: The research utilized 70% perchloric acid in the sample preparation process, demonstrating its efficacy in the analysis of cosmetic products for regulatory and quality control purposes (Yao et al., 1998).
  • Colorimetric determination of hydroxyurea in human serum using high-performance liquid chromatography.: This article describes a colorimetric method involving 70% perchloric acid for sample preparation, which is crucial in clinical chemistry for monitoring hydroxyurea levels in patients (Manouilov et al., 1998).
  • Application of biological samples treated by wet-digested mineralization to cation-exchange high-performance liquid chromatography with post-column reaction by 4-(2-pyridylazo)-resorcinol.: This study details the use of 70% perchloric acid in the mineralization of biological samples, essential for accurate trace metal analysis in biological research (Sudo et al., 1991).
  • Colorimetric micromethods for glutaraldehyde determination by means of phenol and sulfuric acid or phenol and perchloric acid.: The research presents a micromethod utilizing 70% perchloric acid for the colorimetric determination of glutaraldehyde, applicable in biochemical and industrial laboratories for safety and quality assessments (Boratynski and Zal, 1990).

Analysis Note

Assay (acidimetric): 70.0 - 72.0 %
Color: ≤ 10 Hazen
Chlorate (ClO₃): ≤ 10 ppm
Chloride (Cl): ≤ 3 ppm
Free chlorine: ≤ 0.5 ppm
Phosphate and Silicate (as SiO₂): ≤ 5 ppm
Sulfate (SO₄): ≤ 10 ppm
Total nitrogen (N): ≤ 10 ppm
Heavy metals (as Pb): ≤ 1 ppm
Ag (Silver): ≤ 0.1 ppm
Al (Aluminium): ≤ 0.05 ppm
As (Arsenic): ≤ 0.05 ppm
Ba (Barium): ≤ 0.02 ppm
Be (Beryllium): ≤ 0.02 ppm
Bi (Bismuth): ≤ 0.1 ppm
Ca (Calcium): ≤ 0.5 ppm
Cd (Cadmium): ≤ 0.05 ppm
Co (Cobalt): ≤ 0.05 ppm
Cu (Copper): ≤ 0.1 ppm
Fe (Iron): ≤ 1.0 ppm
Ge (Germanium): ≤ 0.05 ppm
Hg (Mercury): ≤ 0.005 ppm
K (Potassium): ≤ 0.1 ppm
Li (Lithium): ≤ 0.02 ppm
Mg (Magnesium): ≤ 0.5 ppm
Mn (Manganese): ≤ 0.02 ppm
Mo (Molybdenum): ≤ 0.05 ppm
Na (Sodium): ≤ 0.5 ppm
Ni (Nickel): ≤ 0.1 ppm
Pb (Lead): ≤ 0.05 ppm
Sr (Strontium): ≤ 0.02 ppm
Ti (Titanium): ≤ 0.1 ppm
Tl (Thallium): ≤ 0.05 ppm
V (Vanadium): ≤ 0.05 ppm
Zn (Zinc): ≤ 0.1 ppm
Zr (Zirconium): ≤ 0.1 ppm
Residue on ignition (as sulfate): ≤ 30 ppm
Identity: passes test
Density (d 20/20): approx. 1.7
Conform to ACS, ISO, Reag.Ph Eur.

Legal Information

EMSURE is a registered trademark of Merck KGaA, Darmstadt, Germany

signalword

Danger

Hazard Classifications

Acute Tox. 4 Oral - Eye Dam. 1 - Met. Corr. 1 - Ox. Liq. 1 - Skin Corr. 1A - STOT RE 2

target_organs

Thyroid

Storage Class

5.1A - Strongly oxidizing hazardous materials

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable


Certificates of Analysis (COA)

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