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1.02066

Supelco

Calcium carbonate

precipitated for analysis EMSURE® Reag. Ph Eur

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About This Item

Linear Formula:
CaCO3
CAS Number:
Molecular Weight:
100.09
Beilstein/REAXYS Number:
8008338
MDL number:
UNSPSC Code:
12352302
EC Index Number:
207-439-9

agency

reag. Ph. Eur.

Quality Level

product line

EMSURE®

assay

98.5-100.5% dry basis (complexometric)

form

solid

potency

6450 mg/kg LD50, oral (Rat)
>2000 mg/kg LD50, skin (Rat)

impurities

≤0.005% Substances insoluble in hydrochloric acid
≤0.2% Substances insoluble in acetic acid

loss

≤ 1.0% loss on drying, 200 °C

particle size

~14 μm (D 50)

pH

9.5-10.5 (20 °C, 100 g/L in H2O, slurry)

mp

825 °C (decomposition)

density

2.93 g/mL at 25 °C (lit.)

bulk density

300‑1400 kg/m3

anion traces

chloride (Cl-): ≤0.005%
sulfate (SO42-): ≤0.03%

cation traces

Al: ≤0.005%
As: ≤0.0004%
Ba:, passes test
Cu: ≤0.0005%
Fe: ≤0.001%
K: ≤0.005%
Mg: ≤0.02%
Mg and allied cations: ≤1.5%
N: ≤0.001%
Na: ≤0.2%
Pb: ≤0.0005%
Sr: ≤0.1%
heavy metals (as Pb): ≤0.002%

storage temp.

10-30°C

SMILES string

[Ca++].[O-]C([O-])=O

InChI

1S/CH2O3.Ca/c2-1(3)4;/h(H2,2,3,4);/q;+2/p-2

InChI key

VTYYLEPIZMXCLO-UHFFFAOYSA-L

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Related Categories

Application


  • Comparison of passive targeted delivery of inorganic and organic nanocarriers among different types of tumors.: This study compares the efficiency of calcium carbonate-based nanocarriers in targeted drug delivery across various tumor types, offering insights into their potential for enhancing cancer treatment efficacy (Postovalova et al., 2024).


Analysis Note

Assay (complexometric; calculated on dried substance): 98.5 - 100.5 %
Identity: passes test
Substances insoluble in acetic acid: ≤ 0.2 %
Substances insoluble in hydrochloric acid: ≤ 0.005 %
Chloride (Cl): ≤ 0.005 %
Sulfate (SO₄): ≤ 0.03 %
Heavy metals (as Pb): ≤ 0.002 %
Total nitrogen (N): ≤ 0.001 %
Al (Aluminium): ≤ 0.005 %
As (Arsenic): ≤ 0.0004 %
Ba (Barium): passes test
Cu (Copper): ≤ 0.0005 %
Fe (Iron): ≤ 0.001 %
K (Potassium): ≤ 0.005 %
Mg (Magnesium): ≤ 0.02 %
Na (Sodium): ≤ 0.2 %
Pb (Lead): ≤ 0.0005 %
Sr (Strontium): ≤ 0.1 %
Magnesium and alkali metals: ≤ 1.5 %
Particle size (d 50): about 14 µm
Loss on drying (200 °C): ≤ 1.0 %
Corresponds to Reag. Ph Eur

Legal Information

EMSURE is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

13 - Non Combustible Solids

wgk_germany

nwg

flash_point_f

Not applicable

flash_point_c

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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