Skip to Content
MilliporeSigma
All Photos(3)

Documents

1.06323

SAFC

Sodium hydrogen carbonate

EMPROVE® ESSENTIAL, Ph. Eur., BP, ChP, JP, USP, FCC, E 500

Pharma Manufacturing

Synonym(s):

Sodium bicarbonate

Sign Into View Organizational & Contract Pricing
All Photos(3)

About This Item

Linear Formula:
NaHCO3
CAS Number:
144-55-8
Molecular Weight:
84.01
Beilstein/REAXYS Number:
4153970
MDL number:
MFCD00003528
UNSPSC Code:
12352302
E Number:
E500
EC Index Number:
205-633-8

agency

BP
ChP
JP
Ph. Eur.
USP

Quality Level

500

reg. compliance

FCC

product line

EMPROVE® ESSENTIAL

form

solid

pH

8.6 (20 °C, 50 g/L in H2O)

pKa (25 °C)

(1) 6.37, (2) 10.25 (carbonic acid)

mp

270 °C (decomposition)

solubility

96 g/L

density

2.22 g/cm3 at 20 °C
2.16 g/mL at 25 °C (lit.)

application(s)

liquid formulation
ophthalmics
pharmaceutical
solid formulation

storage temp.

2-30°C

SMILES string

[Na+].OC([O-])=O

InChI

1S/CH2O3.Na/c2-1(3)4;/h(H2,2,3,4);/q;+1/p-1

InChI key

UIIMBOGNXHQVGW-UHFFFAOYSA-M

Looking for similar products? Visit Product Comparison Guide

Related Categories

General description

Finding the right excipient that matches your needs as well as regulatory demands can be a complicated challenge in formulation. With our application know-how and regulatory expertise, we support you in every step of development, scale-up, and production.
As part of our Emprove® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Application

Sodium hydrogen carbonate is a commonly used ingredient in both food and pharmaceutics. In pharmaceutical applications, sodium hydrogen carbonate is used as pH adjuster, or a source of carbon dioxide in oral formulations such as effervescent tablets or granules.

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Customers Also Viewed

Slide 1 of 5

1 of 5

D-(+)-Glucose EMPROVE® EXPERT, Ph. Eur., BP, JP, USP

SAFC

1.08346

D-(+)-Glucose

Sodium chloride EMPROVE® ESSENTIAL, Ph. Eur., BP, USP

SAFC

1.06400

Sodium chloride

Calcium chloride dihydrate EMPROVE® API, Ph. Eur., BP, ChP, JP, USP

SAFC

1.02465

Calcium chloride dihydrate

Sodium bicarbonate powder, BioReagent, for molecular biology, suitable for cell culture, suitable for insect cell culture

Sigma-Aldrich

S5761

Sodium bicarbonate

Potassium hydrogen carbonate EMPROVE® ESSENTIAL, Ph. Eur., BP, USP, FCC, E 501

SAFC

1.04852

Potassium hydrogen carbonate

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service