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MilliporeSigma

1.06431

SAFC

tri-Sodium citrate 5,5-hydrate

EMPROVE® ESSENTIAL, E 331

Pharma Manufacturing

Synonym(s):

tri-Sodium citrate 5,5-hydrate

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About This Item

Empirical Formula (Hill Notation):
C6H5Na3O7 · 5.5H2O
CAS Number:
Molecular Weight:
357.15
MDL number:
UNSPSC Code:
12352107
E Number:
E331
EC Index Number:
200-675-3

Quality Level

description

FU VIII grade

product line

EMPROVE® ESSENTIAL

form

solid

pH

7.5-9.0 (20 °C, 50 g/L in H2O)

mp

>150 °C (anhydrous)

solubility

920 g/L

application(s)

liquid formulation
ophthalmics
pharmaceutical
semi-solid formulation
solid formulation

storage temp.

2-30°C

InChI

1S/11C6H8O7.11Na.2H2O/c11*7-3(8)1-6(13,5(11)12)2-4(9)10;;;;;;;;;;;;;/h11*13H,1-2H2,(H,7,8)(H,9,10)(H,11,12);;;;;;;;;;;;2*1H2/q;;;;;;;;;;;11*+1;;/p-33

InChI key

HEFYJRQSMQOKRW-UHFFFAOYSA-A

General description

Finding the right excipient that matches your needs as well as regulatory demands can be a complicated challenge in formulation. With our application know-how and regulatory expertise, we support you in every step of development, scale-up, and production.
As part of our Emprove® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Application

Tri-sodium citrate 5,5-hydrate is widely used in pharmaceutical formulations, typically as pH adjuster and buffer agent.

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

related product

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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