Skip to Content
MilliporeSigma
All Photos(1)

Documents

1.07164

Sigma-Aldrich

Paraffin pastilles

solidification point about 56-58°C for histology

Synonym(s):

Paraffin pastilles, Paraffin pastilles solidification point, Paraffin for Histology

Sign Into View Organizational & Contract Pricing


About This Item

CAS Number:
UNSPSC Code:
41116124
EC Index Number:
265-154-5
NACRES:
NA.21

Quality Level

form

solid

potency

>5000 mg/kg LD50, oral (Rat)
>3000 mg/kg LD50, skin (Rabbit)

IVD

for in vitro diagnostic use

color

white

kinematic viscosity

4.2 cSt(100 °C)

transition temp

flash point >100 °C

density

0.9 g/cm3 at 20 °C

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

15-25°C

General description

Paraffin pastilles - solidification point about 56-58 °C for histology, are a highly pure ready-to-use paraffin product. Paraffins are the materials generally used to embed the specimens for histological applications. In order to achieve uniformous ribbon-sectioning quality, defined hardness and homogeneity of the processed material is necessary. This can be guarranteed through high-quality raw materials and defined melting points. The melting point of Paraffin is 56-58°C. It is registered as IVD and CE certified product and can be used for clinical diagnostics. For more details, please see instructions for use (IFU).

Application


  • Clinical application of targeted tumour sequencing tests for detecting ERBB2 amplification and optimizing anti-HER2 therapy in gastric cancer.: This study demonstrates the use of paraffin-embedded tissue samples in targeted tumor sequencing to identify patients suitable for anti-HER2 therapy, highlighting paraffin′s utility in preserving sample integrity for genetic analysis (Ichikawa et al., 2024).

  • Novel FFPE proteomics method suggests prolactin induced protein as hormone induced cytoskeleton remodeling spatial biomarker.: Describes a novel proteomics method using formalin-fixed paraffin-embedded (FFPE) samples to identify biomarkers for hormone-induced changes in cellular structures, advancing tissue-specific molecular diagnostics (Faktor et al., 2024).

  • TSWIFT, a novel method for iterative staining of embedded and mounted human brain sections.: Introduces TSWIFT, a new technique for the iterative staining of paraffin-embedded human brain sections, providing enhanced imaging capabilities for neurological research (Porter et al., 2024).

  • [Optimal melanin removal methods for HE staining, immunohistochemistry and molecular detection].: Investigates various methods for melanin removal in HE staining processes involving paraffin-embedded samples, crucial for accurate histopathological and immunohistochemical analyses (Zhang et al., 2024).

  • Novel Histopathological Findings of Micro Bone Fragments and Epithelial Response in the Oral Mucosa in Bisphosphonate-Related Osteonecrosis of the Jaw.: This case report utilizes paraffin-embedded sections to uncover novel histopathological insights into osteonecrosis, demonstrating paraffin′s role in detailed structural analysis in pathological conditions (Koizumi et al., 2024).

Storage Class

11 - Combustible Solids

wgk_germany

nwg

flash_point_f

Not applicable

flash_point_c

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Customers Also Viewed

Slide 1 of 3

1 of 3

Sigma-Aldrich

Sigma-Aldrich

76242

Paraffin wax

vibrant-m

Y0000913

Paraffin (White soft)

Paraffin wax mp ≥65 °C (ASTM D 87)

Sigma-Aldrich

411663

Paraffin wax

Related Content

Learn about the criticality of biological tissue staining for research and clinical pathology using standard and special stains and dyes.

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service